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monoclonal antibody L6

Known as: L6, MoAb L6 
A murine IgG2a monoclonal antibody with potential antineoplastic activity. Monoclonal antibody L6 binds to the L6 antigen, a cell surface… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1969-2017
05101519692017

Related topics

Related topics

5 relations
Antibody-Dependent Cellular CytotoxicityComplement-Dependent CytotoxicityRPL6 geneTM4SF1 protein, human
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Related mentions per year

Related mentions per year

1957-2018
1960198020002020
monoclonal antibody L6
Antibody-Dependent Cellular Cytotoxicity
antigen binding
Complement-Dependent Cytotoxicity
TM4SF1 protein, human
RPL6 gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2008
2008
Dexamethasone and corticosterone induce similar, but not identical, muscle wasting responses in cultured L6 and C2C12 myotubes.
Dexamethasone-treated L6 (a rat cell line) and C2C12 (a mouse cell line) myotubes are frequently used as in vitro models of… (More)
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2007
2007
Palmitate induced mitochondrial deoxyribonucleic acid damage and apoptosis in l6 rat skeletal muscle cells.
A major characteristic of type 2 diabetes mellitus (T2DM) is insulin resistance in skeletal muscle. A growing body of evidence… (More)
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2006
2006
Colocalization of MCT1, CD147, and LDH in mitochondrial inner membrane of L6 muscle cells: evidence of a mitochondrial lactate oxidation complex.
Results of previous studies suggested a role of mitochondria in intracellular and cell-cell lactate shuttles. Therefore, by using… (More)
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2003
2003
Tumor-associated antigen L6 and the invasion of human lung cancer cells.
Metastasis is a coordinated process that depends on the interaction of cancer cells with the tumor microenvironment. Members of… (More)
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1994
1994
Chemical and Physical Stability of Chimeric L6, a Mouse−Human Monoclonal Antibody
Chimeric L6 is a mouse–human monoclonal antibody specific for tumor cell-associated antigens. The factors affecting the physical… (More)
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1994
1994
The biologic window for chimeric L6 radioimmunotherapy.
BACKGROUND There has been little success in using radioimmunotherapy in patients with adenocarcinoma, partly because of the low… (More)
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1993
1993
Phase I trial of chimeric (human-mouse) monoclonal antibody L6 in patients with non-small-cell lung, colon, and breast cancer
We report a single institution phase I trial of chimeric (mouse-human) monoclonal antibody (chL6) directed against a tumor… (More)
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1990
1990
Phase I trial of murine monoclonal antibody L6 in breast, colon, ovarian, and lung cancer.
Murine monoclonal antibody (MAb) L6 binds to an antigen expressed on the surface of breast, colon, ovary, and nonsmall-cell lung… (More)
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Highly Cited
1989
Highly Cited
1989
Differential expression of myogenic determination genes in muscle cells: possible autoactivation by the Myf gene products.
The development of muscle cells involves the action of myogenic determination factors. In this report, we show that human… (More)
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1986
1986
Antitumor effects of L6, an IgG2a antibody that reacts with most human carcinomas.
Mouse monoclonal antibody L6 (IgG2a subtype) recognizes a ganglioside antigen expressed at the surface of cells from human non… (More)
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