mitochondrial translocation

OBSOLETE. The translocation of proteins across the mitochondrial membrane. In the presence of a translocating chain, the outer membrane import… (More)
National Institutes of Health

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Highly Cited
2011
Highly Cited
2011
The Bcl2/adenovirus E1B 19-kDa interacting protein 3 (Bnip3) is an atypical BH3-only protein that is associated with… (More)
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Highly Cited
2010
Highly Cited
2010
Loss of the E3 ubiquitin ligase Parkin causes early onset Parkinson's disease, a neurodegenerative disorder of unknown etiology… (More)
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Highly Cited
2010
Highly Cited
2010
Huntington's disease (HD), a genetic neurodegenerative disease caused by a polyglutamine expansion in the Huntingtin (Htt… (More)
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Highly Cited
2007
Highly Cited
2007
A major function of the p53 tumor suppressor is the induction of a pleiotropic apoptotic program in response to stress through… (More)
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Highly Cited
2006
Highly Cited
2006
Mitochondrial translocation of pro-apoptotic Bax prior to apoptosis is well established after treatment with many cell death… (More)
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Highly Cited
2004
Highly Cited
2004
p73, an important developmental gene, shares a high sequence homology with p53 and induces both G(1) cell cycle arrest and… (More)
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Highly Cited
2004
Highly Cited
2004
OBJECTIVES We investigated the effects of erbB2 inhibition by anti-erbB2 antibody on cardiomyocyte survival and mitochondrial… (More)
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Highly Cited
2003
Highly Cited
2003
Increasing evidence suggests that movement of key proteins in or out of mitochondria during apoptosis is essential for the… (More)
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Highly Cited
1999
Highly Cited
1999
IL-7 functions as a trophic factor during T lymphocyte development by a mechanism that is partly based on the induction of Bcl-2… (More)
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Highly Cited
1997
Highly Cited
1997
Preprotein import into mitochondria is mediated by translocases located in the outer and inner membranes (Tom and Tim) and a… (More)
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