mitochondrial translocation

OBSOLETE. The translocation of proteins across the mitochondrial membrane. In the presence of a translocating chain, the outer membrane import… (More)
National Institutes of Health

Related topics

Related topics

3 relations

Broader (1)

Mitochondria

Narrower (1)

protein import into mitochondrial matrix
protein targeting to mitochondrion

Papers overview

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Highly Cited
2011
Highly Cited
2011
Mitochondrial autophagy by Bnip3 involves Drp1-mediated mitochondrial fission and recruitment of Parkin in cardiac myocytes.
The Bcl2/adenovirus E1B 19-kDa interacting protein 3 (Bnip3) is an atypical BH3-only protein that is associated with… (More)
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Highly Cited
2010
Highly Cited
2010
Drosophila parkin requires PINK1 for mitochondrial translocation and ubiquitinates mitofusin.
Loss of the E3 ubiquitin ligase Parkin causes early onset Parkinson's disease, a neurodegenerative disorder of unknown etiology… (More)
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Highly Cited
2010
Highly Cited
2010
Mitochondrial fission and cristae disruption increase the response of cell models of Huntington's disease to apoptotic stimuli
Huntington's disease (HD), a genetic neurodegenerative disease caused by a polyglutamine expansion in the Huntingtin (Htt… (More)
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Highly Cited
2007
Highly Cited
2007
Monoubiquitylation promotes mitochondrial p53 translocation.
A major function of the p53 tumor suppressor is the induction of a pleiotropic apoptotic program in response to stress through… (More)
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Highly Cited
2006
Highly Cited
2006
JNK- and p38 kinase-mediated phosphorylation of Bax leads to its activation and mitochondrial translocation and to apoptosis of human hepatoma HepG2 cells.
Mitochondrial translocation of pro-apoptotic Bax prior to apoptosis is well established after treatment with many cell death… (More)
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Highly Cited
2004
Highly Cited
2004
p73 Induces apoptosis via PUMA transactivation and Bax mitochondrial translocation.
p73, an important developmental gene, shares a high sequence homology with p53 and induces both G(1) cell cycle arrest and… (More)
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Highly Cited
2004
Highly Cited
2004
Inhibition of ErbB2 causes mitochondrial dysfunction in cardiomyocytes: implications for herceptin-induced cardiomyopathy.
OBJECTIVES We investigated the effects of erbB2 inhibition by anti-erbB2 antibody on cardiomyocyte survival and mitochondrial… (More)
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Highly Cited
2003
Highly Cited
2003
Mitochondrial translocation of cofilin is an early step in apoptosis induction
Increasing evidence suggests that movement of key proteins in or out of mitochondria during apoptosis is essential for the… (More)
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Highly Cited
1999
Highly Cited
1999
Withdrawal of IL-7 induces Bax translocation from cytosol to mitochondria through a rise in intracellular pH.
IL-7 functions as a trophic factor during T lymphocyte development by a mechanism that is partly based on the induction of Bcl-2… (More)
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Highly Cited
1997
Highly Cited
1997
The Tim core complex defines the number of mitochondrial translocation contact sites and can hold arrested preproteins in the absence of matrix Hsp70-Tim44.
Preprotein import into mitochondria is mediated by translocases located in the outer and inner membranes (Tom and Tim) and a… (More)
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