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Mitochondria
Known as:
Mitochondrial
, Mitochondrion
Semiautonomous, self-reproducing organelles that occur in the cytoplasm of all cells of most, but not all, eukaryotes. Mitochondria contain…
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National Institutes of Health
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Related topics
Related topics
50 relations
A-Kinase Anchor Protein 10, Mitochondrial
ABCB6 protein, human
AMACR protein, human
ATPase WRNIP1
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Narrower (10)
Mitochondria, Heart
Mitochondria, Liver
Mitochondrial chromosome
Mitochondrial nucleoid
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Broader (1)
Organelles
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2010
Highly Cited
2010
PINK1 Is Selectively Stabilized on Impaired Mitochondria to Activate Parkin
Derek P. Narendra
,
S. Jin
,
+5 authors
R. Youle
PLoS Biology
2010
Corpus ID: 11882491
Mutations in PINK1 or Parkin lead to familial parkinsonism. The authors suggest that PINK1 and Parkin form a pathway that senses…
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Review
2010
Review
2010
Targeting mitochondria for cancer therapy
S. Fulda
,
L. Galluzzi
,
G. Kroemer
Nature reviews. Drug discovery
2010
Corpus ID: 14643750
Mitochondria are the cells' powerhouse, but also their suicidal weapon store. Dozens of lethal signal transduction pathways…
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Review
2008
Review
2008
How mitochondria produce reactive oxygen species
M. Murphy
Biochemical Journal
2008
Corpus ID: 7977231
The production of ROS (reactive oxygen species) by mammalian mitochondria is important because it underlies oxidative damage in…
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Highly Cited
2008
Highly Cited
2008
Parkin is recruited selectively to impaired mitochondria and promotes their autophagy
Derek P. Narendra
,
Atsushi Tanaka
,
D. Suen
,
R. Youle
Journal of Cell Biology
2008
Corpus ID: 16473231
Loss-of-function mutations in Park2, the gene coding for the ubiquitin ligase Parkin, are a significant cause of early onset…
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Highly Cited
2008
Highly Cited
2008
Mitofusin 2 tethers endoplasmic reticulum to mitochondria
O. Brito
,
L. Scorrano
Nature
2008
Corpus ID: 4347673
Juxtaposition between endoplasmic reticulum (ER) and mitochondria is a common structural feature, providing the physical basis…
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Review
2004
Review
2004
The incomplete natural history of mitochondria
J. Ballard
,
M. Whitlock
Molecular Ecology
2004
Corpus ID: 5499973
Mitochondrial DNA (mtDNA) has been used to study molecular ecology and phylogeography for 25 years. Much important information…
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Review
2003
Review
2003
Mitochondrial formation of reactive oxygen species
J. Turrens
Journal of Physiology
2003
Corpus ID: 39747667
The reduction of oxygen to water proceeds via one electron at a time. In the mitochondrial respiratory chain, Complex IV…
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Review
2001
Review
2001
The expanding role of mitochondria in apoptosis.
X. Wang
Genes & Development
2001
Corpus ID: 29489407
The initial insight into the genetic basis of apoptosis, or programmed cell death, was gained from ingenious studies of the…
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Highly Cited
1998
Highly Cited
1998
Cleavage of BID by Caspase 8 Mediates the Mitochondrial Damage in the Fas Pathway of Apoptosis
Honglin Li
,
Hong Zhu
,
Chi-jie Xu
,
Junying Yuan
Cell
1998
Corpus ID: 11373542
Highly Cited
1997
Highly Cited
1997
Prevention of Apoptosis by Bcl-2: Release of Cytochrome c from Mitochondria Blocked
Jie Yang
,
X. Liu
,
+6 authors
Xiaodong Wang
Science
1997
Corpus ID: 32349676
Bcl-2 is an integral membrane protein located mainly on the outer membrane of mitochondria. Overexpression of Bcl-2 prevents…
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