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protein targeting to mitochondrion
Known as:
protein import into mitochondrion
, mitochondrial protein import
, protein-mitochondrial targeting
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The process of directing proteins towards and into the mitochondrion, usually mediated by mitochondrial proteins that recognize signals contained…
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National Institutes of Health
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Related topics
Related topics
7 relations
mitochondrial translocation
negative regulation of protein targeting to mitochondrion
Broader (1)
mitochondrion organization
Narrower (4)
protein import into mitochondrial inner membrane
protein import into mitochondrial intermembrane space
protein import into mitochondrial matrix
protein import into mitochondrial outer membrane
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2013
Highly Cited
2013
A role for sequestosome 1/p62 in mitochondrial dynamics, import and genome integrity.
M. Seibenhener
,
Yifeng Du
,
Maria T. Diaz-Meco
,
J. Moscat
,
Michael C. Wooten
,
M. W. Wooten
Biochimica et Biophysica Acta
2013
Corpus ID: 23783268
2012
2012
Mitochondrial protein import pathways are functionally conserved among eukaryotes despite compositional diversity of the import machineries
Elisabeth Eckers
,
M. Cyrklaff
,
L. Simpson
,
Marcel Deponte
Biological chemistry
2012
Corpus ID: 17497679
Abstract Mitochondrial protein import (MPI) is essential for the biogenesis of mitochondria in all eukaryotes. Current models of…
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Review
2008
Review
2008
Unusual cellular disposition of the mitochondrial molecular chaperones Hsp60, Hsp70 and Hsp10.
Radhey S. Gupta
,
N. Ramachandra
,
T. Bowes
,
Bhag Singh
Novartis Foundation symposium
2008
Corpus ID: 29253402
A number of molecular chaperones in mammalian cells are localized in mitochondria and they are presumed to function mainly within…
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2003
2003
Functional consequences of thyroid hormone-induced changes in the mitochondrial protein import pathway.
Marco Colavecchia
,
L. N. Christie
,
Y. Kanwar
,
D. Hood
American Journal of Physiology. Endocrinology and…
2003
Corpus ID: 12440616
Thyroid hormone [3,5,3'-triiodo-l-thyronine (T(3))] induces phenotypic alterations in cardiac mitochondria, in part by…
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1999
1999
Characterization of the novel mitochondrial protein import component, Tom34, in mammalian cells.
N. Chewawiwat
,
M. Yano
,
K. Terada
,
N. Hoogenraad
,
Masataka Mori
Journal of Biochemistry (Tokyo)
1999
Corpus ID: 46005668
Tom34 is a newly-found component of the mitochondrial protein import machinery in mammalian cells with no apparent counterpart in…
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Highly Cited
1997
Highly Cited
1997
Visualization of Mitochondrial Protein Import in Cultured Mammalian Cells with Green Fluorescent Protein and Effects of Overexpression of the Human Import Receptor Tom20*
M. Yano
,
M. Kanazawa
,
+5 authors
M. Mori
Journal of Biological Chemistry
1997
Corpus ID: 35843370
The presequence of the ornithine transcarbamylase precursor (pOTC) was fused to green fluorescent protein (GFP), yielding pOTC…
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Highly Cited
1996
Highly Cited
1996
The mitochondrial protein import motor: Dissociation of mitochondrial hsp70 from its membrane anchor requires ATP binding rather than ATP hydrolysis
M. Horst
,
W. Oppliger
,
Bastian Feifel
,
G. Schatz
,
B. Glick
Protein Science
1996
Corpus ID: 13132174
During protein import into mitochondria, matrix‐localized mitochondrial hsp70 (mhsp70) interacts with the inner membrane protein…
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Highly Cited
1995
Highly Cited
1995
A human homolog of the mitochondrial protein import receptor Mom19 can assemble with the yeast mitochondrial receptor complex
N. Seki
,
M. Moczko
,
+6 authors
N. Pfanner
FEBS Letters
1995
Corpus ID: 45148104
Highly Cited
1993
Highly Cited
1993
Mas6p can be cross-linked to an arrested precursor and interacts with other proteins during mitochondrial protein import.
K. Ryan
,
R. Jensen
Journal of Biological Chemistry
1993
Corpus ID: 34461912
Mas6p is an integral membrane protein of the yeast mitochondrial inner membrane, which is essential for mitochondrial protein…
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Highly Cited
1988
Highly Cited
1988
Role of ATP in mitochondrial protein import. Conformational alteration of a precursor protein can substitute for ATP requirement.
N. Pfanner
,
R. Pfaller
,
Ralf Kleene
,
Masaki Ito
,
M. Tropschug
,
Walter Neupert
Journal of Biological Chemistry
1988
Corpus ID: 19635010
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