FAQ

protein targeting to mitochondrion

Known as: protein import into mitochondrion, mitochondrial protein import, protein-mitochondrial targeting 
The process of directing proteins towards and into the mitochondrion, usually mediated by mitochondrial proteins that recognize signals contained… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1982-2017
05101519822017

Related topics

Related topics

6 relations
mitochondrial translocation

Broader (1)

mitochondrion organization

Narrower (4)

protein import into mitochondrial inner membraneprotein import into mitochondrial intermembrane spaceprotein import into mitochondrial matrixprotein import into mitochondrial outer membrane

Related mentions per year

Related mentions per year

1973-2018
197019801990200020102020
protein targeting to mitochondrion
mitochondrial translocation
mitochondrion organization
protein import into mitochondrial inner membrane
protein import into mitochondrial outer membrane
protein import into mitochondrial intermembrane space

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2014
2014
Inhibition of mitochondrial protein import by mutant huntingtin
Mitochondrial dysfunction is associated with neuronal loss in Huntington's disease (HD), a neurodegenerative disease caused by an… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
2012
2012
Mitochondrial protein import: from transport pathways to an integrated network.
Mitochondria, the powerhouses of the cell, import most of their proteins from the cytosol. It was originally assumed that… (More)
  • figure 1
  • figure 2
Is this relevant?
2009
2009
Tim23–Tim50 pair coordinates functions of translocators and motor proteins in mitochondrial protein import
Mitochondrial protein traffic requires coordinated operation of protein translocator complexes in the mitochondrial membrane. The… (More)
Is this relevant?
Highly Cited
2006
Highly Cited
2006
Mutation of DNAJC19, a human homologue of yeast inner mitochondrial membrane co-chaperones, causes DCMA syndrome, a novel autosomal recessive Barth syndrome-like condition.
BACKGROUND A novel autosomal recessive condition, dilated cardiomyopathy with ataxia (DCMA) syndrome, has been identified in the… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
2005
2005
Pam17 is required for architecture and translocation activity of the mitochondrial protein import motor.
Import of mitochondrial matrix proteins involves the general translocase of the outer membrane and the presequence translocase of… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
2004
Highly Cited
2004
A transcriptomic and proteomic characterization of the Arabidopsis mitochondrial protein import apparatus and its response to mitochondrial dysfunction.
Mitochondria import hundreds of cytosolically synthesized proteins via the mitochondrial protein import apparatus. Expression… (More)
  • figure 1
  • figure 2
  • figure 3
  • table I
  • table II
Is this relevant?
1989
1989
A 42K outer-membrane protein is a component of the yeast mitochondrial protein import site.
An engineered precursor protein that sticks in the import site of isolated yeast mitochondria can be specifically photo… (More)
Is this relevant?
1989
1989
Mitochondrial protein import. Bypass of proteinaceous surface receptors can occur with low specificity and efficiency.
Proteolytic degradation of receptor sites on the mitochondrial surface strongly reduces the efficiency of mitochondrial protein… (More)
Is this relevant?
1987
1987
Both ATP and an energized inner membrane are required to import a purified precursor protein into mitochondria.
We have investigated the energy requirement of mitochondrial protein import with a simplified system containing only isolated… (More)
Is this relevant?
Highly Cited
1987
Highly Cited
1987
Mitochondrial protein import: nucleoside triphosphates are involved in conferring import-competence to precursors.
The role of nucleoside triphosphates (NTPs) in mitochondrial protein import was investigated with the precursors of N. crassa ADP… (More)
Is this relevant?