microcin B17
National Institutes of Health
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Microcin B17 (MccB17) is a post-translationally modified peptide containing thiazole and oxazole heterocycles that interrupt the…
The total synthesis of the 43 amino acid antibacterial peptide Microcin B17 (MccB17) is described. The natural product was…
Microbes employ several catalytic strategies to transform conformationally flexible peptide chains into rigidified scaffolds that…
The discovery of the peptide DNA gyrase inhibitor microcin B17 (MccB17) in the early 1990s provided a new tool and hope for a…
Abstract Previous studies [Connell et al. (1987) Mol Microbiol 1: 195–201] have shown that expression of the microcin B17 (MccB17…
Microcin B17 (McB17), the first known gyrase inhibitor of peptidic nature, is produced by ribosomal synthesis and post…
The maturation pathway of microcin B17 (MccB17), a ribosomally synthesized peptide antibiotic which inhibits DNA gyrase, has been…