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mevinolinic acid

Known as: lovestatin acid 
National Institutes of Health

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2 relations

Broader (1)

Lovastatin
analogs & derivatives

Papers overview

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1997
1997
Quantitative analysis of mevinolinic acid in human plasma by high-performance liquid chromatography coupled with negative-ion electrospray tandem mass spectrometry.
Mevinolinic acid (MVA), the major active metabolite of Lovastatin in human blood, is analysed by microbore high-performance… 
1995
1995
[Action of lovastatin--an inhibitor of cholesterol biosynthesis on bacterial bioluminescence].
The action of lovastatin, a competing inhibitor of 3-hydroxy-3-methylglutaryl CoA reductase, on bacterial bioluminescence was… 
Highly Cited
1990
Highly Cited
1990
Regulation of bile acid synthesis. IV. Interrelationship between cholesterol and bile acid biosynthesis pathways.
Under most experimental conditions, the activities of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA reductase) and cholesterol 7… 
1990
1990
Regulation of bile acid synthesis. V. Inhibition of conversion of 7-dehydrocholesterol to cholesterol is associated with down-regulation of cholesterol 7 alpha-hydroxylase activity and inhibition of…
In the chronic bile fistula rat, the administration of a bolus dose of mevinolinic acid, an inhibitor of HMG-CoA reductase, was… 
Review
1983
Review
1983
A new era of exploitation of microbial metabolites.
In the past history of the pharmaceutical industry, secondary metabolites have been screened almost exclusively for antimicrobial… 
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