FAQ

methylmalonyl-CoA decarboxylase

Known as: Methylmalonyl-CoA Decarboxylase [Chemical/Ingredient], Methylmalonyl CoA Decarboxylase, Propionyl-CoA Carboxylase 
A carboxy-lyase that catalyzes the decarboxylation of (S)-2-Methyl-3-oxopropanoyl-CoA to propanoyl-CoA. In microorganisms the reaction can be coupled… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1977-2017
012319772017

Related topics

Related topics

13 relations

Broader (3)

Carbon-Carbon LigasesCarboxy-LyasesLigase
In BloodProcess of secretionPropionic acidemiaadministration & dosage
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Related mentions per year

Related mentions per year

1936-2018
19401960198020002020
methylmalonyl-CoA decarboxylase
physiological aspects
Ligase
Carboxy-Lyases
chemical synthesis
Propionic acidemia

Papers overview

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Highly Cited
2014
Highly Cited
2014
Phylogenetic distribution of three pathways for propionate production within the human gut microbiota
Propionate is produced in the human large intestine by microbial fermentation and may help maintain human health. We have… (More)
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2011
2011
Ethylmalonyl-CoA decarboxylase, a new enzyme involved in metabolite proofreading.
A limited number of enzymes are known that play a role analogous to DNA proofreading by eliminating non-classical metabolites… (More)
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2010
2010
Investigating the role of native propionyl-CoA and methylmalonyl-CoA metabolism on heterologous polyketide production in Escherichia coli.
6-Deoxyerythronolide B (6dEB) is the macrocyclic aglycone precursor of the antibiotic natural product erythromycin. Heterologous… (More)
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1993
1993
Sequence of the sodium ion pump methylmalonyl-CoA decarboxylase from Veillonella parvula.
The genes encoding methylmalonyl-CoA decarboxylase from Veillonella parvula were cloned on plasmids using oligonucleotides… (More)
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1991
1991
On the mechanism of sodium ion translocation by methylmalonyl-CoA decarboxylase from Veillonella alcalescens.
Veillonella alcalescens during lactate degradation developed an Na+ concentration gradient with 7-8 times higher external than… (More)
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1989
1989
The carboxyltransferase activity of the sodium-ion-translocating methylmalonyl-CoA decarboxylase of Veillonella alcalescens.
Methylmalonyl-CoA decarboxylase of Veillonella alcalescens catalyzed the isotopic exchange between methylmalonyl-CoA and [1-14C… (More)
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1984
1984
Reconstitution of Na+ transport from purified methylmalonyl-CoA decarboxylase and phospholipid vesicles.
Methylmalonyl-CoA decarboxylase from Veillonella alcalescens which was isolated by affinity chromatography on avidin-Sepharose… (More)
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Highly Cited
1984
Highly Cited
1984
Life by a new decarboxylation-dependent energy conservation mechanism with Na as coupling ion.
We report here a new mode of ATP synthesis in living cells. The anaerobic bacterium Propionigenium modestum gains its total… (More)
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1983
1983
Purification and characterization of a new sodium-transport decarboxylase. Methylmalonyl-CoA decarboxylase from Veillonella alcalescens.
Upon resolution of the particulate cell fraction of Veillonella alcalescens by gel chromatography, membranes and ribosomes were… (More)
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1977
1977
Propionyl-CoA Carboxylase Deficiency in a Patient with Biotin-responsive 3-Methylcrotonylglycinuria
Summary: The abnormal metabolites 3-hydroxypropionic acid (1.6–4.0 mg/day) and methylcitric acid (3.7–5.8 mg/day) were identified… (More)
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