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methylazoxymethanol

Known as: methazoxymethanol 
National Institutes of Health

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Broader (4)

Alkylating AgentsCarcinogensMethylazoxymethanol AcetateTeratogens
analogs & derivatives

Papers overview

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1997
1997
Apoptosis induced by methylazoxymethanol in developing rat cerebellum: organization of the cell nucleus and its relationship to DNA and rRNA degradation
Abstract.We present a cytological and biochemical study of the cell death of granule cell precursors in developing rat cerebellum… 
Highly Cited
1994
Highly Cited
1994
Developmental neurotoxicity: evaluation of testing procedures with methylazoxymethanol and methylmercury.
Testing procedures for identification of potential developmental neurotoxicants were evaluated using two prototypical… 
1992
1992
Premature decline in Morris water maze performance of aging micrencephalic rats.
1991
1991
Treatment with methylazoxymethanol at different gestational days: physical, reflex development and spontaneous activity in the offspring.
Pregnant rats were injected with a single dose of methylazoxymethanol (MAM, 25 mg/kg) on gestational day 14, 15, 16, 17, 18 or 19… 
1985
1985
Methylazoxymethanol as a developmental model of neurotoxicity.
Behavioral consequences of exposure to toxic chemicals during development often depend on critical periods of exposure. The… 
Highly Cited
1980
Highly Cited
1980
Elevated Monoamine Levels in the Cerebral Hemispheres of Microencephlic Rats Treated Prenatally with Methylazoxymethanol or Cytosine Arabinoside
Abstract: Methylazoxymethanol (MAM) injection to rats on day 15 of gestation caused a significant rise in monoamine… 
Highly Cited
1976
Highly Cited
1976
Postnatal maturation of rat Purkinje cells cultivated in the absence of two afferent systems: An ultrastructural study
Organized cultures of newborn rat cerebellum were established in Maximow chambers in order to study the maturation of Purkinje… 
Highly Cited
1969
Highly Cited
1969
Studies on Methylazoxymethanol
Summary Methylazoxymethanol, the aglycone of cycasin, reacted with nucleic acids and proteins in the fetus of rats injected with… 
Highly Cited
1968
Highly Cited
1968
Transplacental Chemical Induction of Microencephaly in Two Strains of Rats. I
Summary An experimental model for successful chemical induction of microencephaly is described. Methylazoxymethanol, the aglycone… 
1967
1967
Teratogenic Effects of Methylazoxymethanol
Summary Methylazoxymethanol (MAM), the aglycone of cycasin, a naturally occurring glucoside of cycad plants, causes retardation… 
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