Methylazoxymethanol Acetate

Known as: (Methyl-ONN-azoxy)methanol Acetate, Acetate, Methylazoxymethanol, Methylazoxymethanol Acetate [Chemical/Ingredient] 
The aglycone of CYCASIN. It acts as a potent carcinogen and neurotoxin and inhibits hepatic DNA, RNA, and protein synthesis.
National Institutes of Health

Topic mentions per year

Topic mentions per year

1968-2018
051019682018

Papers overview

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Highly Cited
2009
Highly Cited
2009
Decreased GABAergic signaling is among the more robust pathologies observed postmortem in schizophrenia; however, the functional… (More)
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2007
2007
Gestational methylazoxymethanol acetate (MAM) exposure has been suggested to produce neural and behavioral abnormalities similar… (More)
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Highly Cited
2007
Highly Cited
2007
Evidence supports a dysregulation of subcortical dopamine (DA) system function as a common etiology of psychosis; however, the… (More)
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Highly Cited
2006
Highly Cited
2006
BACKGROUND As a test of plausibility for the hypothesis that schizophrenia can result from abnormal brain, especially cerebral… (More)
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2005
2005
During adulthood, new neurons are continuously added to the mammalian dentate gyrus (DG). An increasing number of studies have… (More)
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Highly Cited
2005
Highly Cited
2005
Although thousands of new neurons are continuously produced in the dentate gyrus of rodents each day, the function of these… (More)
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2005
2005
Prenatal methylazoxymethanol acetate (MAM) treatment has been shown to induce morphological abnormalities in cortical areas of… (More)
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Highly Cited
2002
Highly Cited
2002
The hippocampal formation generates new neurons throughout adulthood. Recent studies indicate that these cells possess the… (More)
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1995
1995
The administration of the alkylating neurotoxin methylazoxymethanol acetate (MAM) to pregnant rats on day 15 of gestation induces… (More)
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1970
1970
Methylazoxymethanol acetate is known to induce tu mors in rodents. Effects produced by a single nonlethal dose on nucleic acid… (More)
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