membrane protein solubilization

 
National Institutes of Health

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membrane protein ectodomain proteolysis

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2015
2015
Impact of Solubilizing Additives on Supersaturation and Membrane Transport of Drugs
Many enabling formulations give rise to supersaturated solutions wherein the solute possesses higher thermodynamic activity… (More)
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2013
2013
Stepwise solubilization-based antigen removal for xenogeneic scaffold generation in tissue engineering.
The ability of residual antigens on decellularized tissue to elicit the immune response upon implantation motivates development… (More)
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2013
2013
Correlation of hydrotropic solubilization by urea with logD of drug molecules and utilization of this effect for topical formulations.
Solubilization of drugs in aqueous phases of liquid and semisolid environment is typically achieved by co-solvents or surfactants… (More)
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2010
2010
Novel application of mixed hydrotropic solubilization technique in the formulation and evaluation of hydrotropic solid dispersion of aceclofenac
Solid dispersion technology[1-9] is one of the method of increasing the dissolution rate, and hence the rate of absorption and/or… (More)
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2010
2010
Molecular dynamics simulations of hydrotropic solubilization and self-aggregation of nicotinamide.
Hydrotropy is a phenomenon where the presence of a large quantity of one solute enhances the solubility of another solute. The… (More)
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2007
2007
Novel application of hydrotropic solubilization in the analysis of some NSAIDs and their solid dosage forms
Quantitative analysis of poorly water-soluble drugs involves use of various organic solvents. Major drawbacks of organic solvents… (More)
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2007
2007
Characterization of β-lapachone and methylated β-cyclodextrin solid-state systems
The purpose of this research was to explore the utility of β cyclodextrin (βCD) and β cyclodextrin derivatives (hydroxypropyl… (More)
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1999
1999
Measurement of mass-transfer rates for surfactant-enhanced solubilization of nonaqueous phase liquids
Surfactant-enhanced solubilization of residual, nonaqueous-phase liquid (NAPL) contaminants is an emerging, subsurface… (More)
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1996
1996
Hydrotropic Solubilization— Mechanistic Studies
Purpose. This study examines the mechanism of hydrotropic solubilization using the riboflavin-nicotinamide system. The most… (More)
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1990
1990
Lignocarbohydrate solubilization from straw by actinomycetes.
Actinomycetes grown on wheat straw solubilized a lignocarbohydrate fraction which could be recovered by acid precipitation… (More)
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