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melarsen oxide
Known as:
melarsenoxide
, p-(4,6-diamino-1,3,5-triazin-2-yl)aminophenylarsonous acid
National Institutes of Health
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Broader (1)
Arsenicals
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2011
2011
Antitumor Quinol PMX464 Is a Cytocidal Anti-trypanosomal Inhibitor Targeting Trypanothione Metabolism*
J. König
,
S. Wyllie
,
G. Wells
,
M. Stevens
,
P. Wyatt
,
A. Fairlamb
Journal of Biological Chemistry
2011
Corpus ID: 205308510
Better drugs are urgently needed for the treatment of African sleeping sickness. We tested a series of promising anticancer…
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2006
2006
The antitrypanosomal drug melarsoprol competitively inhibits thiamin uptake in mouse neuroblastoma cells
Piotr Szyniarowski
,
L. Bettendorff
,
M. Schweingruber
Cell Biology and Toxicology
2006
Corpus ID: 8377368
Melarsoprol is the main drug used for the treatment of late-stage sleeping sickness, although it causes severe side-effects such…
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2004
2004
The Melaminophenyl Arsenicals Melarsoprol and Melarsen Oxide Interfere with Thiamine Metabolism in the Fission Yeast Schizosaccharomyces pombe
M. Schweingruber
Antimicrobial Agents and Chemotherapy
2004
Corpus ID: 29496112
ABSTRACT The melaminophenyl arsenical melarsoprol is the main drug used against late-stage sleeping sickness caused by…
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2000
2000
A potential target enzyme for trypanocidal drugs revealed by the crystal structure of NAD-dependent glycerol-3-phosphate dehydrogenase from Leishmania mexicana.
S. Suresh
,
S. Turley
,
F. Opperdoes
,
P. Michels
,
W. Hol
Structure
2000
Corpus ID: 2700419
1997
1997
Trypanosoma brucei: lack of cross-resistance to melarsoprol in vitro by cymelarsan-resistant parasites.
Alan G. Scott
,
Andy Tait
,
C. Turner
Experimental parasitology
1997
Corpus ID: 36834095
We have examined cross-resistance between trypanocidal drugs using a well-characterised drug-sensitive line, 247, and its…
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1996
1996
The importance of 2,3-dimercaptopropinol (British anti-lewisite, BAL) in the trypanocidal activity of topical melarsoprol.
F. Jennings
,
J. Atouguia
,
M. Murray
Acta Tropica
1996
Corpus ID: 28619224
1994
1994
Induction of resistance to melarsenoxide cysteamine (Mel Cy) in Trypanosoma brucei brucei.
H. Pospichal
,
R. Brun
,
R. Kaminsky
,
L. Jenni
Acta Tropica
1994
Corpus ID: 35237544
1994
1994
Properties of melarsamine hydrochloride (Cymelarsan) in aqueous solution
Bradley J. Berger
,
A. Fairlamb
Antimicrobial Agents and Chemotherapy
1994
Corpus ID: 35915238
The antitrypanosomal drug melarsamine hydrochloride (MelCy) (trade name, Cymelarsan) is a melamino-phenylarsine made by…
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1994
1994
High-performance liquid chromatographic method for the separation and quantitative estimation of anti-parasitic melaminophenyl arsenical compounds.
B. Berger
,
A. Fairlamb
Transactions of the Royal Society of Tropical…
1994
Corpus ID: 8695326
1992
1992
The interaction of arsenical drugs with dihydrolipoamide and dihydrolipoamide dehydrogenase from arsenical resistant and sensitive strains of Trypanosoma brucei brucei.
A. Fairlamb
,
K. Smith
,
K. Hunter
Molecular and biochemical parasitology (Print)
1992
Corpus ID: 4035333
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