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IgE, mast cells, basophils, and eosinophils are essential components of allergic inflammation. Antigen-specific IgE production… Expand Exosomes are vesicles of endocytic origin released by many cells. These vesicles can mediate communication between cells… Expand This review focuses on recent progress in our understanding of how mast cells can contribute to the initiation, development… Expand Mast cells are so widely recognized as critical effector cells in allergic disorders and other immunoglobulin E–associated… Expand ConclusionsThere is good evidence for mast cell heterogeneity both in the rat model and in the human. The rat and human differ… Expand Mast cells have mainly been studied in the setting of allergic disease, but the importance of mast cells for host defence against… Expand BACKGROUND
Asthma and eosinophilic bronchitis are characterized by similar inflammatory infiltrates in the submucosa of the lower… Expand ALTHOUGH mast cells have been implicated in a variety of inflammatory conditions including immediate hypersensitivity and… Expand IN many cell types, receptor-mediated Ca2+ release from internal stores is followed by Ca2+ influx across the plasma membrane1–3… Expand A panel of antigen-specific mouse helper T cell clones was characterized according to patterns of lymphokine activity production… Expand