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mannosyl-oligosaccharide 1,2-alpha-mannosidase activity

Known as: man9-mannosidase activity, 1,2-alpha-mannosidase, mannosidase I 
Catalysis of the hydrolysis of the terminal (1->2)-linked alpha-D-mannose residues in an oligo-mannose oligosaccharide. [GOC:bf, PMID:25092655]
National Institutes of Health

Related topics

Related topics

4 relations
MAN1B1 genemannosyl-oligosaccharide 1,2-alpha-mannosidase

Narrower (1)

ManI activity

Broader (1)

alpha-mannosidase activity

Papers overview

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2015
2015
MAN1B1 Mutation Leads to a Recognizable Phenotype: A Case Report and Future Prospects
Intellectual disability (ID) is one of the most common reasons for referral to genetic counseling. Nevertheless, in over 50% of… 
Highly Cited
2015
Highly Cited
2015
High-resolution mass spectrometry glycoprofiling of intact transferrin for diagnosis and subtype identification in the congenital disorders of glycosylation.
Highly Cited
2008
Highly Cited
2008
Effects of macromolecular crowding on glycoprotein processing enzymes.
Intracellular environments are highly crowded due to the presence of various biomacromolecules. In this study, we estimated the… 
2007
2007
Molecular Cloning and Expression of a cDNA Encoding a Coccidioides posadasii 1,2‐α‐Mannosidase Identified in the Coccidioidal T27K Vaccine by Immunoproteomic Methods
Abstract:  The coccidioidal T27K vaccine is protective in mice against respiratory challenge with Coccidioides posadasii (C… 
2006
2006
Cloning and Expression of 1,2-α-Mannosidase Gene (fmanIB) from Filamentous Fungus Aspergillus oryzae: in Vivo Visualization of the FmanIBp-GFP Fusion Protein
1,2-α-Mannosidase catalyzes the specific cleavage of 1,2-α-mannose residues from protein-linked N-glycan. In this study, a novel… 
Review
2000
Review
2000
Unique Catalytic and Molecular Properties of Hydrolases from Aspergillus used in Japanese Bioindustries
This review covers the unique catalytic and molecular properties of three proteolytic enzymes and a glycosidase from Aspergillus… 
Highly Cited
1999
Highly Cited
1999
Identification, Expression, and Characterization of a cDNA Encoding Human Endoplasmic Reticulum Mannosidase I, the Enzyme That Catalyzes the First Mannose Trimming Step in Mammalian Asn-linked…
We have isolated a full-length cDNA clone encoding a human α1,2-mannosidase that catalyzes the first mannose trimming step in the… 
1998
1998
Overproduction of 1,2-alpha-mannosidase, a glycochain processing enzyme, by Aspergillus oryzae.
A recombinant strain of Aspergillus oryzae has been constructed in which 1,2-alpha-mannosidase, an intracellular glycochain… 
1993
1993
1,2-alpha-D-mannosidase from Penicillium citrinum: molecular and enzymic properties of two isoenzymes.
Two isoforms of acidic 1,2-alpha-D-mannosidases have been isolated from culture filtrate of Penicillium citrinum. The pI values… 
1986
1986
Improved purification of Aspergillus oryzae 1,2-alpha-mannosidase by using mannan gel affinity chromatography.
In order to facilitate the purification of 1,2-alpha-mannosidase from an enzyme product of Aspergillus oryzae, we have devised a… 
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