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macrophage fusion

The binding and fusion of a macrophage to one or more other cells to form a multinucleated cell. [GOC:sl]
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2011
Review
2011
Macrophage fusion and multinucleated giant cells of inflammation.
Macrophages undergo fusion with other macrophages to form the hallmark multinucleated giant cells of chronic inflammation… 
Review
2009
Review
2009
Molecular mediators of macrophage fusion.
Highly Cited
2009
Highly Cited
2009
The scavenger receptor CD36 plays a role in cytokine-induced macrophage fusion
Multinucleated giant cells, characteristic of granulomatous infections, originate from the fusion of macrophages. Using an… 
Highly Cited
2007
Highly Cited
2007
Macrophage fusion induced by IL‐4 alternative activation is a multistage process involving multiple target molecules
Multinucleated giant cells, characteristic of granulomatous infections, originate from fusion of macrophages, however, little is… 
Highly Cited
2004
Highly Cited
2004
The CC chemokine ligand, CCL2/MCP1, participates in macrophage fusion and foreign body giant cell formation.
Review
2000
Review
2000
Osteoclasts and giant cells: macrophage–macrophage fusion mechanism
  • A. Vignery
  • International journal of experimental pathology…
  • 2000
  • Corpus ID: 11724037
Membrane fusion is a ubiquitous event that occurs in a wide range of biological processes. While intracellular membrane fusion… 
Highly Cited
2000
Highly Cited
2000
CD47, a Ligand for the Macrophage Fusion Receptor, Participates in Macrophage Multinucleation*
The macrophage fusion receptor (MFR), also called P84/BIT/SIRPα/SHPS-1, is a transmembrane glycoprotein that belongs to the… 
Highly Cited
1998
Highly Cited
1998
MFR, a Putative Receptor Mediating the Fusion of Macrophages
ABSTRACT We had previously identified a macrophage surface protein whose expression is highly induced, transient, and specific… 
Highly Cited
1997
Highly Cited
1997
Interleukin-13 induces human monocyte/macrophage fusion and macrophage mannose receptor expression.
Inasmuch as we recently demonstrated that IL-4 is a strong inducer of monocyte/macrophage fusion and IL-13 has been observed to… 
Highly Cited
1995
Highly Cited
1995
Interleukin-4 induces foreign body giant cells from human monocytes/macrophages. Differential lymphokine regulation of macrophage fusion leads to morphological variants of multinucleated giant cells.
Interleukin-4 induced the formation of foreign body-type giant multinucleated cells from human monocyte-derived macrophages, an… 
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