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macelignan

Known as: (8R,8'S)-7-(3,4-Methylenedioxyphenyl)-7'-(4-Hydroxy-3-Methoxyphenyl)-8,8'-Dimethylbutane, Phenol, 4-((2s,3r)-4-(1,3-Benzodioxol-5-Yl)-2,3-Dimethylbutyl)-2-Methoxy- 
A lignan isolated from nutmeg with antimicrobial and anticariogenic activity against Streptococcus mutans and other streptococcus species.
National Institutes of Health

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Lignans

Papers overview

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2016
2016
The in Silico Study of Nutmeg Seeds (Myristica fragrans Houtt) as Peroxisome Proliferator Activated Receptor Gamma Activator Using 3D-QSAR Pharmacophore Modelling
In this study, we created pharmacophore models from a dataset of agonists for PPAR gamma receptor using the Catalyst/Hypogen… 
2013
2013
Dibenzylbutane Lignans from the Stems of Schisandra Bicolor
Further investigation of the stems of Schisandra bicolor led to the isolation of a new dibenzylbutane lignan, named… 
2012
2012
Macelignan Inhibits Histamine Release and Inflammatory Mediator Production in Activated Rat Basophilic Leukemia Mast Cells
Type I allergy is characterized by the release of granule-associated mediators, lipid-derived substances, cytokines, and… 
2010
2010
Effect of maceligan on the systemic exposure of paclitaxel: in vitro and in vivo evaluation.
2010
2010
In vitro and in vivo analysis of macelignan induced toxicity on heart
Macelignan which isolated from Myristica fragrans Houtt has been suggested that it acts as PPAR α/γ dual agonist for diabetic… 
2010
2010
The Hypoglycemic Effect of Complex of Chinese Traditional Herbs (CTH) and Macelignan in Type 2 Diabetic Animal Model
This study investigated the efficacy of macelignan and hot water with Chinese traditional herb (CTH) extract on altering severe… 
2010
2010
Inhibition of Urokinase-Type Plasminogen Activator Expression by Macelignan in Porphyromonas gingivalis Supernatant-Induced Human Oral Epithelial Cells
This study was to investigate the effect of macelignan on Porphyromonas gingivalis supernatant-induced uPA expression via… 
2008
2008
Determination of macelignan in rat plasma by high-performance liquid chromatography with ultraviolet detection
A high-performance liquid chromatographic method was developed for the determination of macelignan in rat plasma and applied to… 
2006
2006
Method of preventing and treating a disease mediated by ppar using macelignan
The present invention relates to a method of treating a disease mediated by PPAR, which comprises administering a macelignan… 
2006
2006
Methods to prevent and treat conditions mediated by PPAR using Macelignan.
Using Macelignan represented by the following formula (I) or a pharmaceutically acceptable salt thereof in the manufacture of a… 
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