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- Prabagar Balakrishnan, Beom-Jin Lee, +8 authors Han-gon Choi
- European journal of pharmaceutics and…
- 2009
The main objective of this study was to prepare a solid form of lipid-based self-emulsifying drug delivery system (SEDDS) by spray drying liquid SEDDS with an inert solid carrier Aerosil 200 to… (More)
- Phuong Ha Lien Tran, Huyen Thi Thanh Tran, Beom-Jin Lee
- Journal of controlled release : official journal…
- 2008
The present work is an original evaluation of the microenvironmental pH (pH(M)) and crystallinity of an ionizable drug in order to enhance its dissolution using alkalizers in polyethylene glycol 6000… (More)
- Chau Le-Ngoc Vo, Chulhun Park, Beom-Jin Lee
- European journal of pharmaceutics and…
- 2013
Over 40% of active pharmaceutical ingredients (API) in development pipelines are poorly water-soluble drugs which limit formulation approaches, clinical application and marketability because of their… (More)
- Hyo-Kyung Han, Beom-Jin Lee, Hyoung-Kyu Lee
- International journal of pharmaceutics
- 2011
The present study aimed to improve the bioavailability of biochanin A, a poorly soluble bioflavonoid, via the preparation of solid dispersion (SD) using Solutol HS15 and HPMC 2910. Solubility of… (More)
- Lai Yuan Liu, Ja Ryong Ku, Gilson Khang, Beom-Jin Lee, John Rhee, Hai Bang Lee
- Journal of controlled release : official journal…
- 2000
The sandwiched osmotic tablet system (SOTS), which is composed of a sandwiched osmotic tablet core surrounded by a cellulose acetate membrane with two orifices on both side surfaces, has been… (More)
- Prabagar Balakrishnan, Beom-Jin Lee, +8 authors Han-gon Choi
- International journal of pharmaceutics
- 2009
To enhance the solubility and bioavailability of poorly water-soluble Coenzyme Q(10) (CoQ(10)), self-emulsifying drug delivery system (SEDDS) composed of oil, surfactant and cosurfactant for oral… (More)
- Chul Soon Yong, Chae Ha Yang, +6 authors Han-gon Choi
- International journal of pharmaceutics
- 2004
To improve the bioavailability of poorly water-soluble ibuprofen in the rectum with poloxamer and menthol, the effects of menthol and poloxamer 188 on the aqueous solubility of ibuprofen were… (More)
- Min-Young Heo, Zong-Zhu Piao, Tae-wan Kim, Qing-Ri Cao, Aera Kim, Beom-Jin Lee
- Archives of pharmacal research
- 2005
Polyethylene glycol (PEG) 6000-based solid dispersions (SDs), by incorporating various pharmaceutical excipients or microemulsion systems, were prepared using a fusion method, to compare the… (More)
- Dong Hoon Oh, Jun Hyeok Kang, +4 authors Han-gon Choi
- International journal of pharmaceutics
- 2011
In order to compare the effects of hydrophilic and hydrophobic solid carrier on the formation of solid self-microemulsifying drug delivery system (SMEDDS), two solid SMEDDS formulations were prepared… (More)
- Thao Truong-Dinh Tran, Phuong Ha-Lien Tran, Beom-Jin Lee
- European journal of pharmaceutics and…
- 2009
We investigated the dissolution-modulating mechanism of alkalizers and polymers in nanoemulsifying Gelucire 44/14 (GUC)-based solid dispersions (SDs) for controlled release. Aceclofenac (AFC), an… (More)