mRNA processing

Any process involved in the conversion of a primary mRNA transcript into one or more mature mRNA(s) prior to translation into polypeptide. [GOC:mah]
National Institutes of Health

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Highly Cited
2014
Highly Cited
2014
Mutations in the gene encoding the RNA-binding protein RBM20 have been implicated in dilated cardiomyopathy (DCM), a major cause… (More)
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2012
2012
Establishing the functional roles of genetic variants remains a significant challenge in the post-genomic era. Here, we present a… (More)
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Highly Cited
2011
Highly Cited
2011
RNA-binding proteins coordinate the fates of multiple RNAs, but the principles underlying these global interactions remain poorly… (More)
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2009
2009
The SWI/SNF chromatin remodeling complexes regulate the transcription of many genes by remodeling nucleosomes at promoter regions… (More)
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Highly Cited
2009
Highly Cited
2009
The CDC73 tumor suppressor gene is mutationally inactivated in hereditary and sporadic parathyroid tumors. Its product, the Cdc73… (More)
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Highly Cited
2008
Highly Cited
2008
HIV-1 provirus, either as a chromosomal integrant or as an episomal plasmid in HeLa cells, forms a transcription-dependent gene… (More)
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Highly Cited
2005
Highly Cited
2005
During 3' end processing, histone pre-mRNAs are cleaved 5 nucleotides after a conserved stem loop by an endonuclease dependent on… (More)
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2004
2004
The chromatin immunoprecipitation (ChIP) technique has been used to determine where and under what conditions DNA binding… (More)
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Review
2002
Review
2002
The messenger RNA processing reactions of capping, splicing, and polyadenylation occur cotranscriptionally. They not only… (More)
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1999
1999
N-myc gene copy numbers and transcription rates are similar in N (neuroblastic, tumorigenic) and S (non-neuronal, non-tumorigenic… (More)
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