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losartan carboxylic acid

Known as: 1H-imidazole-5-carboxylic acid, 2-butyl-4-chloro-1-((2'-(2H-tetrazol-5-yl)(1,1'-biphenyl)-4-yl)methyl)-, 2-n-butyl-4-chloro-1-((2'-(1H-tetrazol-5-yl)biphenyl-4-yl)methylll)imidazole-5-carboxylic acid 
National Institutes of Health

Related topics

Related topics

4 relations

Broader (3)

Anti-Arrhythmia AgentsAntihypertensive AgentsLosartan

Narrower (1)

EXP3174

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Brain delivery of losartan carboxylic acid and evaluation of its efficacy against stress induced neurodegeneration
2017
2017
[LB.03.10] PHARMACOMETABOLOMIC ANALYZES OF FIVE ANTIHYPERTENSIVE DRUGS FROM HUMAN SERUM SAMPLES OF RESISTANT HYPERTENSIVE PATIENTS
Objective: Our aim was to analyze the serum measurements of five antihypertensive drugs (enalapril and its active metabolite… 
2017
2017
High-throughput quanti fi cation of 8 antihypertensive drugs and active metabolites in human plasma using UPLC – MS / MS
Background: To assess drug adherence of patients with hypertension, an analytical method was developed and validated using ultra… 
2016
2016
Postmortem blood concentrations of sartans measured by liquid chromatography-tandem mass spectrometry
A liquid chromatography-tandem mass spectrometric (LC–MS/MS) method was developed and validated for the analysis of seven common… 
2015
2015
Human Bioequivalence Evaluation of Two Losartan Potassium Tablets Under Fasting Conditions
The bioequivalence of two different tablet formulations containing losartan potassium 100 mg was determined in healthy volunteers… 
2012
2012
Development of a HPLC method for the determination of losartan urinary metabolic ratio to be used for the determination of CYP2C9 hydroxylation phenotypes
Abstract Background: Losartan is metabolized to losartan carboxylic acid (E-3174) by the polymorphic cytochrome CYP2C9. The aim… 
2010
2010
Pharmaceutical compositions and a method of manufacturing the containing losartan carboxylic acid
Disclosed is a pharmaceutical composition containing losartan carboxylic acid and a preparing method thereof. The pharmaceutical… 
2009
2009
Bioequivalence model for evaluation of Losartan in human plasma with special reference to drug–metabolite ratio
Losartan and in-vivo active metabolite losartan carboxylic acid (LCA) formation into systemic circulation have been poorly… 
2005
2005
Comparative pharmacokinetics of two tablet formulations of Losartan: bioequivalence assessment
The pharmacokinetic profiles of two brands of losartan 50 mg tablets were compared in 24 healthy adult volunteers after a single… 
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