Author pages are created from data sourced from our academic publisher partnerships and public sources.
- Publications
- Influence
Effects of Ginkgo Biloba Extract on Pharmacokinetics and Pharmacodynamics of Tolbutamide and Midazolam in Healthy Volunteers
This study was undertaken to clarify the influence of repeated oral administration of Ginkgo biloba extract (GBE) on CYP2C9 and CYP3A4. CYP2C9 probe (tolbutamide, 125 mg) and CYP3A4 probe (midazolam,… Expand
Physicochemical and pharmacological characterization of alpha-tocopherol-loaded nano-emulsion system.
- J. Hatanaka, Hina Chikamori, +4 authors S. Yamada
- Chemistry, Medicine
- International journal of pharmaceutics
- 30 August 2010
The main purpose of the present study is to develop a novel nano-emulsion (NE) formulation of alpha-tocopherol (alpha-TC) with enhanced oral bioavailability and pharmacological effects. Three NE… Expand
Brain neurotransmitter receptor-binding characteristics in rats after oral administration of haloperidol, risperidone and olanzapine.
The present study was conducted to characterize the binding of neurotransmitter receptors (dopamine D(2), serotonin 5-HT(2), histamine H(1), adrenaline alpha(1) and muscarine M(l) receptors) in the… Expand
Relationship between brain serotonin transporter binding, plasma concentration and behavioural effect of selective serotonin reuptake inhibitors
- K. Hirano, R. Kimura, +5 authors S. Yamada
- Chemistry, Medicine
- British journal of pharmacology
- 1 March 2005
1 The present study was undertaken to characterise the relationship between in vivo brain serotonin transporter (SERT) binding, plasma concentration and pharmacological effect of selective serotonin… Expand
Brain pharmacokinetics and in vivo receptor binding of 1,4-dihydropyridine calcium channel antagonists.
- S. Uchida, S. Yamada, K. Nagai, Y. Deguchi, R. Kimura
- Chemistry, Medicine
- Life sciences
- 17 October 1997
Brain pharmacokinetics of 1,4-dihydropyridine (DHP) calcium channel antagonists and their in vivo receptor binding in mice were characterized. The area under the concentration vs time curve… Expand
Antinociceptive effects of St. John's wort, Harpagophytum procumbens extract and Grape seed proanthocyanidins extract in mice.
- S. Uchida, K. Hirai, J. Hatanaka, Junko Hanato, K. Umegaki, S. Yamada
- Chemistry, Medicine
- Biological & pharmaceutical bulletin
- 1 February 2008
Hypericum perforatum extract (St. John's wort, SJW), Harpagophytum procumbens extract (HPE) and Grape seed proanthocyanidin extract (GSPE) have a broad spectrum of biological activities including… Expand
Effect of granule properties on rough mouth feel and palatability of orally disintegrating tablets.
- Shin-ichiro Kimura, S. Uchida, K. Kanada, N. Namiki
- Materials Science, Medicine
- International journal of pharmaceutics
- 30 April 2015
In this study, we evaluated the palatability of orally disintegrating tablets (ODTs) containing core granules with different particle sizes, coating, and types of materials using visual analog scales… Expand
Effects of cigarette smoking and cytochrome P450 2D6 genotype on fluvoxamine concentration in plasma of Japanese patients.
- Yasuhiro Katoh, S. Uchida, +7 authors H. Hashimoto
- Medicine
- Biological & pharmaceutical bulletin
- 1 February 2010
Fluvoxamine is a selective serotonin reuptake inhibitor widely used in the treatment of depression and other psychiatric diseases. The aim of this study was to assess the clinical impact of cigarette… Expand
Comparison of inhibitory duration of grapefruit juice on organic anion-transporting polypeptide and cytochrome P450 3A4.
- S. Tanaka, S. Uchida, +4 authors N. Namiki
- Chemistry, Medicine
- Biological & pharmaceutical bulletin
- 1 December 2013
Recently, a new type of interaction has been reported in which fruit juices diminish oral drug bioavailability through inhibition of organic anion-transporting polypeptide (OATP). In this study, we… Expand
Binding activities by propiverine and its N-oxide metabolites of L-type calcium channel antagonist receptors in the rat bladder and brain.
- S. Uchida, Souhei Kurosawa, +4 authors S. Yamada
- Chemistry, Medicine
- Life sciences
- 6 June 2007
The present study was undertaken to characterize the binding activities of propiverine and its N-oxide metabolites (1-methyl-4-piperidyl diphenylpropoxyacetate N-oxide: P-4(N-->O),… Expand
...
1
2
3
4
5
...