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lophotoxin
Known as:
11,16,18,19-Tetraoxapentacyclo(12.2.2.16,9.01,15.010,12)nonadeca-6,8-diene-7-carboxaldehyde, 2-(acetyloxy)-12-methyl-4-(1-methylethenyl)-17-oxo-, (1R-(1R*,2S*,4S*,10R*,12R*,14R*,15R*))-
National Institutes of Health
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1 relation
Broader (1)
Terpenes
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2006
2006
LOPHOTOXIN BLOCKS SYNAPTIC ACETYLCHOLINE RECEPTORS IN THE COCKROACH PERIPLANETA AMERICANA
J. Blagburn
,
D. Sattelle
2006
Corpus ID: 8031501
The actions of lophotoxin on synaptic acetylcholine receptors were investigated, using the cholinergic synapse between the…
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1996
1996
Lophotoxin-insensitive nematode nicotinic acetylcholine receptors.
C. Tornøe
,
L. Holden-Dye
,
C. Garland
,
S. Abramson
,
J. Fleming
,
D. Sattelle
Journal of Experimental Biology
1996
Corpus ID: 2871390
Nematode nicotinic acetylcholine receptors (nAChRs) are molecular targets of several anthelmintic drugs. Studies to date on…
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1995
1995
Irreversible inhibitors of nicotinic acetylcholine receptors: isolation and structural characterization of the biologically active solvolysis products of bipinnatin-A and bipinnatin-C.
E. Hyde
,
A. Boyer
,
P. Tang
,
Y. Xu
,
S. Abramson
Journal of Medicinal Chemistry
1995
Corpus ID: 22759528
The lophotoxins irreversibly inhibit nicotinic acetylcholine receptors by covalent modification of Tyr190 in the alpha-subunits…
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1995
1995
Evidence for a carbocation intermediate during conversion of bipinnatin-A and -C into irreversible inhibitors of nicotinic acetylcholine receptors.
E. Hyde
,
S. M. Thornhill
,
A. Boyer
,
S. Abramson
Journal of Medicinal Chemistry
1995
Corpus ID: 43175789
The lophotoxins are naturally occurring antagonists of nicotinic acetylcholine receptors. These toxins are small diterpenes that…
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1993
1993
Actions of a coral toxin analogue (bipinnatin-B) on an insect nicotinic acetylcholine receptor.
D. Bai
,
S. Abramson
,
D. Sattelle
Archives of Insect Biochemistry and Physiology
1993
Corpus ID: 31071426
The lophotoxin analogue, bipinnatin-B, is a potent neurotoxin isolated from the gorgonian coral Pseudopterogorgia bipinnata. When…
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1987
1987
Lophotoxin: Selective blockade of nicotinic transmission in autonomic ganglia by a coral neurotoxin
E. Sorenson
,
P. Culver
,
V. Chiappinelli
Neuroscience
1987
Corpus ID: 23343740
1984
1984
Endplate blocking actions of lophotoxin
W. Atchison
,
T. Narahashi
,
S. Vogel
British Journal of Pharmacology
1984
Corpus ID: 38965639
1 Effects of lophotoxin (LTX), a neurotoxin isolated from Pacific sea whips Lophogorgia rigida and Lophogorgia chelensis, on…
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1983
1983
A revised model of the molecular structure of the acetylcholine receptor at the neuromuscular junction.
J. Smythies
Medical Hypotheses
1983
Corpus ID: 41987022
1983
1983
Quantal analysis indicates an alpha-toxin-like block by lophotoxin, a non-ionic marine natural product.
R. B. Langdon
,
R. Jacobs
Life Science
1983
Corpus ID: 31330160
1981
1981
Lophotoxin: a neuromuscular acting toxin from the sea whip (Lophogorgia rigida).
P. Culver
,
R. Jacobs
Toxicon
1981
Corpus ID: 41863870
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