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lophotoxin
Known as:
11,16,18,19-Tetraoxapentacyclo(12.2.2.16,9.01,15.010,12)nonadeca-6,8-diene-7-carboxaldehyde, 2-(acetyloxy)-12-methyl-4-(1-methylethenyl)-17-oxo-, (1R-(1R*,2S*,4S*,10R*,12R*,14R*,15R*))-
National Institutes of Health
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1 relation
Broader (1)
Terpenes
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2006
2006
LOPHOTOXIN BLOCKS SYNAPTIC ACETYLCHOLINE RECEPTORS IN THE COCKROACH PERIPLANETA AMERICANA
J. Blagburn
,
D. Sattelle
2006
Corpus ID: 8031501
The actions of lophotoxin on synaptic acetylcholine receptors were investigated, using the cholinergic synapse between the…
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2005
2005
Synthetic studies towards furanocembrane diterpenes. A total synthesis of bis-deoxylophotoxin.
M. Cases
,
Felix Gonzalez-Lopez de Turiso
,
M. Hadjisoteriou
,
G. Pattenden
Organic and biomolecular chemistry
2005
Corpus ID: 38961663
Synthetic approaches to the furanocembrane family of natural products, e.g. lophotoxins, pukalides, bipinnatins, based on: i) an…
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2002
2002
Synthesis of the C(1)-C(18) segment of lophotoxin and pukalide. Control of 2-alkenylfuran (E/Z)-configuration.
P. Wipf
,
M. Soth
Organic Letters
2002
Corpus ID: 40690517
[reaction: see text] The convergent synthesis of the fully functionalized C(1)-C(18) segment 24 of the furanocembranes lophotoxin…
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1996
1996
Lophotoxin-insensitive nematode nicotinic acetylcholine receptors.
C. Tornøe
,
L. Holden-Dye
,
C. Garland
,
S. Abramson
,
J. Fleming
,
D. Sattelle
Journal of Experimental Biology
1996
Corpus ID: 2871390
Nematode nicotinic acetylcholine receptors (nAChRs) are molecular targets of several anthelmintic drugs. Studies to date on…
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1995
1995
Evidence for a carbocation intermediate during conversion of bipinnatin-A and -C into irreversible inhibitors of nicotinic acetylcholine receptors.
E. Hyde
,
S. M. Thornhill
,
A. Boyer
,
S. Abramson
Journal of Medicinal Chemistry
1995
Corpus ID: 43175789
The lophotoxins are naturally occurring antagonists of nicotinic acetylcholine receptors. These toxins are small diterpenes that…
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1987
1987
Lophotoxin: Selective blockade of nicotinic transmission in autonomic ganglia by a coral neurotoxin
E. Sorenson
,
P. Culver
,
V. Chiappinelli
Neuroscience
1987
Corpus ID: 23343740
1985
1985
Irreversible autonomic actions by lophotoxin suggest utility as a probe for both C6 and C10 nicotinic receptors
R. B. Langdon
,
R. Jacobs
Brain Research
1985
Corpus ID: 10350892
1984
1984
Endplate blocking actions of lophotoxin
W. Atchison
,
T. Narahashi
,
S. Vogel
British Journal of Pharmacology
1984
Corpus ID: 38965639
1 Effects of lophotoxin (LTX), a neurotoxin isolated from Pacific sea whips Lophogorgia rigida and Lophogorgia chelensis, on…
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1983
1983
A revised model of the molecular structure of the acetylcholine receptor at the neuromuscular junction.
J. Smythies
Medical Hypotheses
1983
Corpus ID: 41987022
1981
1981
Lophotoxin: a neuromuscular acting toxin from the sea whip (Lophogorgia rigida).
P. Culver
,
R. Jacobs
Toxicon
1981
Corpus ID: 41863870
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