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lophotoxin

Known as: 11,16,18,19-Tetraoxapentacyclo(12.2.2.16,9.01,15.010,12)nonadeca-6,8-diene-7-carboxaldehyde, 2-(acetyloxy)-12-methyl-4-(1-methylethenyl)-17-oxo-, (1R-(1R*,2S*,4S*,10R*,12R*,14R*,15R*))- 
National Institutes of Health

Papers overview

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Review
2001
Review
2001
Neuronal nicotinic acetylcholine receptors are distributed extensively throughout the central and peripheral nervous systems… Expand
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Review
2000
Review
2000
  • H. Arias
  • Neurochemistry International
  • 2000
  • Corpus ID: 21771162
Identification of all residues involved in the recognition and binding of cholinergic ligands (e.g. agonists, competitive… Expand
1995
1995
Lophotoxin and the bipinnatins are members of the lophotoxin family of marine neurotoxins, which covalently react with Tyr in the… Expand
Highly Cited
1994
Highly Cited
1994
Sequence analysis reveals unique features in the alpha-subunit of nicotinic acetylcholine receptors from the alpha-toxin… Expand
1991
1991
Lophotoxin is a small cyclic diterpene that irreversibly inhibits agonist binding to nicotinic acetylcholine receptors by… Expand
Highly Cited
1990
Highly Cited
1990
Neuronal and muscle nicotinic acetylcholine receptor subunit combinations expressed in Xenopus oocytes were tested for… Expand
Highly Cited
1989
Highly Cited
1989
Lophotoxin and lophotoxin analog-1 are natural diterpenes from coral that inhibit nicotinic acetylcholine receptors by covalent… Expand
1988
1988
Lophotoxin and lophotoxin analog-1 are uncharged cyclic diterpenes obtained from gorgonian corals. They have been shown to block… Expand
1984
1984
Lophotoxin, a cyclic diterpenoid isolated from coral, irreversibly inactivates the nicotinic acetylcholine receptor on intact… Expand
Highly Cited
1981
Highly Cited
1981
A new neuromuscular toxin, lophotoxin, has been isolated from several pacific gorgonians of the genus Lophogorgia. The structure… Expand