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Neuronal nicotinic acetylcholine receptors are distributed extensively throughout the central and peripheral nervous systems… Expand Identification of all residues involved in the recognition and binding of cholinergic ligands (e.g. agonists, competitive… Expand Lophotoxin and the bipinnatins are members of the lophotoxin family of marine neurotoxins, which covalently react with Tyr in the… Expand Sequence analysis reveals unique features in the alpha-subunit of nicotinic acetylcholine receptors from the alpha-toxin… Expand Lophotoxin is a small cyclic diterpene that irreversibly inhibits agonist binding to nicotinic acetylcholine receptors by… Expand Neuronal and muscle nicotinic acetylcholine receptor subunit combinations expressed in Xenopus oocytes were tested for… Expand Lophotoxin and lophotoxin analog-1 are natural diterpenes from coral that inhibit nicotinic acetylcholine receptors by covalent… Expand Lophotoxin and lophotoxin analog-1 are uncharged cyclic diterpenes obtained from gorgonian corals. They have been shown to block… Expand Lophotoxin, a cyclic diterpenoid isolated from coral, irreversibly inactivates the nicotinic acetylcholine receptor on intact… Expand A new neuromuscular toxin, lophotoxin, has been isolated from several pacific gorgonians of the genus Lophogorgia. The structure… Expand