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lixazinone

Known as: Butanamide, N-cyclohexyl-N-methyl-4-((1,2,3,5-tetrahydro-2-oxoimidazo(2,1-b)quinazolin-7-yl)oxy)-, N-cyclohexyl-N-methyl-4-(7-oxy-1,2,3,5-tetrahydroimidazo(2,1-b)quinazolin-2-one)butyramide 
National Institutes of Health

Related topics

Related topics

2 relations

Broader (1)

Quinazolines

Narrower (1)

RS 82856

Papers overview

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2013
2013
Rapid Publication Suppression of Mesangial Proliferative Glomerulonephritis Development in Rats by Inhibitors of cAMP Phosphodiesterase Isozymes Types III and IV
Excessive mesangial cell (MC) proliferation is a hallmark of many glomerulopathies. In our recent study on cultured rat MC… 
2007
2007
Signaling role of PDE isozymes in pathobiology of glomerular mesangial cells
Mesangial cells (MC) of renal glomeruli respond to immune-inflammatory injury by accelerated proliferation and generation of… 
Highly Cited
2000
Highly Cited
2000
Functions of the N-terminal Region of Cyclic Nucleotide Phosphodiesterase 3 (PDE 3) Isoforms*
The N-terminal portion of phosphodiesterase (PDE) 3 was arbitrarily divided into region 1 (amino acids 1–300), which contains a… 
1997
1997
Inhibitors of cyclic nucleotide phosphodiesterase isozymes block renal tubular cell proliferation induced by folic acid.
1997
1997
Expression and mutagenesis of the catalytic domain of cGMP-inhibited phosphodiesterase (PDE3) cloned from human platelets.
We have used reverse transcriptase PCR, platelet mRNA and degenerate primers based on platelet peptide sequences, to amplify a… 
1994
1994
Photoaffinity labelling of cyclic GMP-inhibited phosphodiesterase (PDE III) in human and rat platelets and rat tissues: effects of phosphodiesterase inhibitors.
1989
1989
Analysis of the binding sites for the cardiotonic phosphodiesterase inhibitor [3H]LY186126 in ventricular myocardium.
The positive inotropic action of the newer cardiotonic phosphodiesterase inhibitors such as indolidan, milrinone, and imazodan… 
1988
1988
Inhibitors of cyclic AMP phosphodiesterase. 4. Synthesis and evaluation of potential prodrugs of lixazinone (N-cyclohexyl-N-methyl-4-[(1,2,3,5-tetrahydro-2- oxoimidazo[2,1-b]quinazolin-7-yl)-oxy…
The cyclic AMP phosphodiesterase (cAMP PDE) inhibitor and cardiotonic agent lixazinone (N-cyclohexyl-N-methyl-4-[(1,2,3,5… 
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