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liarozole fumarate
Known as:
(+-)-5-(m-Chloro-alpha-imidazol-1-ylbenzyl)benzimidazole Fumarate (2:3)
, 1H-Benzimidazole, 5-((3-chlorophenyl)-1H-imidazol-1-ylmethyl)-, (+-)-, (E)-2-butenedioate (2:3)
The orally active fumarate salt of the benzimidazole derivative liarozole with potential antineoplastic activity. As a retinoic acid metabolism…
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National Institutes of Health
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2 relations
Narrower (1)
R85246
Broader (1)
liarozole
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2006
2006
Effects of liarozole fumarate (R85246) in combination with tamoxifen on N-methyl-N-nitrosourea Title: (MNU)-induced mammary carcinoma and uterus in the rat model Authors:
P. Goss
,
K. Strasser
,
+5 authors
H. Thompson
2006
Corpus ID: 102492685
2005
2005
Gateways to clinical trials.
M. Bayés
,
X. Rabasseda
,
J. Prous
Methods and Findings in Experimental and Clinical…
2005
Corpus ID: 40550722
Gateways to Clinical Trials is a guide to the most recent clinical trials reported in current literature and congresses. The data…
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2003
2003
In vitro evaluation of chemopreventive agents using cultured human prostate epithelial cells.
X. Wan
,
Zhoazong Zhou
,
A. Kennedy
,
L. Kopelovich
Oncology Report
2003
Corpus ID: 25912801
The effects of nine potential cancer chemopreventive agents on cell growth or clonogenic survival were evaluated in normal human…
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1999
1999
Liarozole. Liarozole fumarate, Liazal, R 75251, R 85246.
Drugs in R&D
1999
Corpus ID: 10190417
1998
1998
EORTC 10941; Final results of a phase II study of liarozole fumarate in patients with metastatic breast cancer
J. Klijn
,
A. Hamilton
,
+7 authors
M. Piccart
1998
Corpus ID: 71746283
1995
1995
A molecular model for the interaction between vorozole and other non-steroidal inhibitors and human cytochrome P450 19 (P450 Aromatase)
L. Koymans
,
H. Moereels
,
H. Bossche
Journal of Steroid Biochemistry and Molecular…
1995
Corpus ID: 13649621
1993
1993
Liarozole and 13-cis-retinoic acid anti-prostatic tumor activity.
M. Stearns
,
M. Wang
,
K. Fudge
Cancer Research
1993
Corpus ID: 8360290
Liarozole fumarate (R85,246), a novel benzimidazole derivative, reduced s.c. and bone metastasis tumor growth by the androgen…
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1993
1993
Liarozole fumarate, an inhibitor of retinoic acid (RA) metabolism with antitumoral activity
R. Coster
,
R. Ginckel
,
+5 authors
M. Coene
1993
Corpus ID: 75749683
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