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levonantradol

A synthetic cannabinoid analogue of delta (9)-tetrahydrocannabinol (delta(9)-THC) with antiemetic and anti-analgesic properties. Although its precise… Expand
National Institutes of Health

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2 relations
Levonantradol HCl

Broader (1)

nantradol

Papers overview

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Highly Cited
2000
Highly Cited
2000
Cannabinoids inhibit LPS-inducible cytokine mRNA expression in rat microglial cells.
The effect of cannabinoids on the induction of cytokine mRNA by rat microglial cells was examined. Exposure of neonatal rat… Expand
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Highly Cited
2000
Highly Cited
2000
Cannabinoid agonist signal transduction in rat brain: comparison of cannabinoid agonists in receptor binding, G-protein activation, and adenylyl cyclase inhibition.
To investigate differences in agonist affinity, potency, and efficacy across rat brain regions, five representative cannabinoid… Expand
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Highly Cited
1992
Highly Cited
1992
Antinociceptive activity of intrathecally administered cannabinoids alone, and in combination with morphine, in mice.
The antinociceptive effects of various cannabinoids, alone and in combination with opiates, were evaluated in antinociceptive… Expand
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Highly Cited
1990
Highly Cited
1990
Pharmacological characterization of cannabinoids in the elevated plus maze.
delta 9-Tetrahydrocannabinol (delta 9-THC) induced in both rats and mice an increased aversion to the open arms of the elevated… Expand
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Highly Cited
1988
Highly Cited
1988
Pharmacology and stereoselectivity of structurally novel cannabinoids in mice.
The pharmacological effects of three stereoisomeric pairs of structurally novel cannabinoids were tested after i.v… Expand
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Highly Cited
1984
Highly Cited
1984
Cannabinoid inhibition of adenylate cyclase. Pharmacology of the response in neuroblastoma cell membranes.
Adenylate cyclase in plasma membranes was inhibited by micromolar concentrations of delta 8-tetrahydrocannabinol and delta 9… Expand
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Highly Cited
1981
Highly Cited
1981
Evaluation of intramuscular levonantradol and placebo in acute postoperative pain.
Double-blind administration of a single intramuscular dose of 1.5, 2.0, 2.5, or 3.0 mg levonantradol or placebo to 56 patients… Expand
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1981
1981
Levonantradol for chemotherapy-induced emesis: phase I-II oral administration.
Thirty five patients were enrolled into a Phase I-II study of oral levonantradol being tested as an antiemetic for chemotherapy… Expand
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1981
1981
Behavioral effects of levonantradol and nantradol in the rhesus monkey.
In rhesus monkeys, acute administration of levonantradol and nantradol produced signs of CNS depression, including ataxia with… Expand
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1981
1981
The antinociceptive effects of intrathecally administered levonantradol and desacetyllevonantradol in the rat.
  • Tony L. Yaksh
  • Journal of clinical pharmacology
  • 1981
    • Corpus ID: 31771251
Levonantradol and its desacetylated metabolite (desacetyllevonantradol) produced a dose-dependent increase in the hot plate and… Expand
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