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levonantradol

A synthetic cannabinoid analogue of delta (9)-tetrahydrocannabinol (delta(9)-THC) with antiemetic and anti-analgesic properties. Although its precise… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1981-2015
0102019812015

Related topics

Related topics

2 relations

Narrower (1)

Levonantradol HCl

Broader (1)

nantradol

Related mentions per year

Related mentions per year

1979-2015
197019801990200020102020
levonantradol
nantradol
Levonantradol HCl

Papers overview

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Highly Cited
2000
Highly Cited
2000
Cannabinoids inhibit LPS-inducible cytokine mRNA expression in rat microglial cells.
The effect of cannabinoids on the induction of cytokine mRNA by rat microglial cells was examined. Exposure of neonatal rat… (More)
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Highly Cited
1990
Highly Cited
1990
Pharmacological characterization of cannabinoids in the elevated plus maze.
delta 9-Tetrahydrocannabinol (delta 9-THC) induced in both rats and mice an increased aversion to the open arms of the elevated… (More)
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Highly Cited
1984
Highly Cited
1984
Cannabinoid inhibition of adenylate cyclase. Pharmacology of the response in neuroblastoma cell membranes.
Adenylate cyclase in plasma membranes was inhibited by micromolar concentrations of delta 8-tetrahydrocannabinol and delta 9… (More)
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1983
1983
The effects of levonantradol on rewarding brain stimulation thresholds in the rat.
Rats were implanted bilaterally with electrodes aimed at the medial forebrain bundle (MFB) and trained to deliver intracranial… (More)
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1981
1981
Evaluation of intramuscular levonantradol and placebo in acute postoperative pain.
Double-blind administration of a single intramuscular dose of 1.5, 2.0, 2.5, or 3.0 mg levonantradol or placebo to 56 patients… (More)
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1981
1981
The antinociceptive effects of intrathecally administered levonantradol and desacetyllevonantradol in the rat.
Levonantradol and its desacetylated metabolite (desacetyllevonantradol) produced a dose-dependent increase in the hot plate and… (More)
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1981
1981
Levonantradol: a role for central prostanoid mechanisms?
Although delta 9-tetrahydrocannabinol (THC) possesses many pharmacologic activities, attempts to define sites of biochemical… (More)
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1981
1981
Levonantradol for chemotherapy-induced emesis: phase I-II oral administration.
Thirty five patients were enrolled into a Phase I-II study of oral levonantradol being tested as an antiemetic for chemotherapy… (More)
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1981
1981
Behavioral effects of levonantradol and nantradol in the rhesus monkey.
In rhesus monkeys, acute administration of levonantradol and nantradol produced signs of CNS depression, including ataxia with… (More)
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1981
1981
A pharmacological analysis of levonantradol antinociception in mice.
Using the hot plate test, the potency and mechanism of the analgesic activity of levonantradol was studied in mice. Levonantradol… (More)
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