leptomycin B

Known as: 2,10,12,16,18-Nonadecapentaenoic acid, 19-(3,6-dihydro-3-methyl-6-oxo-2H-pyran-2-yl)-17-ethyl-6-hydroxy-3,5,7,9,11,15-hexamethyl-8-oxo-, elactocin 
 
National Institutes of Health

Papers overview

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Highly Cited
2013
Highly Cited
2013
The polyketide natural product Leptomycin B inhibits nuclear export mediated by the karyopherin protein chromosomal region… (More)
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Highly Cited
2007
Highly Cited
2007
Sir2 (silent information regulator 2) is an NAD(+)-dependent histone deacetylase that contributes to longevity in yeast. SIRT1, a… (More)
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Highly Cited
2006
Highly Cited
2006
Cloning of the entire set of an organism's protein-coding open reading frames (ORFs), or 'ORFeome', is a means of connecting the… (More)
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Highly Cited
2004
Highly Cited
2004
We introduce a novel statistical approach that quantifies, for the first time, the amount of colocalization of two fluorescent… (More)
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Highly Cited
2003
Highly Cited
2003
Cyclooxygenase (COX)-2, the inducible prostaglandin synthase, is overexpressed in cancer and chronic inflammatory diseases. Post… (More)
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Highly Cited
2002
Highly Cited
2002
We aimed to investigate the dynamics of the NF-kappaB signaling pathway in living cells using GFP variants of p65-NF-kappaB… (More)
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2001
2001
We have studied nuclear export of influenza virus components using an in vitro transport system with digitonin-treated infected… (More)
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Highly Cited
2000
Highly Cited
2000
AU-rich elements (AREs) present in the 3' untranslated regions of many protooncogene, cytokine, and lymphokine messages target… (More)
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Highly Cited
1999
Highly Cited
1999
Appropriate subcellular localization is crucial for regulating p53 function. We show that p53 export is mediated by a highly… (More)
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Highly Cited
1998
Highly Cited
1998
UNLABELLED To study the intracellular localization of MAPKAP kinase 2 (MK2), which carries a putative bipartite nuclear… (More)
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