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leiodermatolide

 
National Institutes of Health

Papers overview

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2017
2017
The C(1)-C(13) fragment of the antimitotic marine macrolide leiodermatolide is prepared in seven steps via hydrogenative and… Expand
2017
2017
Two new analogues of the potent antitumor compound leiodermatolide, which we call leiodermatolides B and C, have been isolated… Expand
2016
2016
Pancreatic cancer, the fourth leading cause of cancer death in the United States, has a negative prognosis because metastasis… Expand
2016
2016
The macrocyclic core (35) of the marine natural product leiodermatolide (1) was synthesized from two key fragments, vinyl iodide… Expand
Highly Cited
2014
Highly Cited
2014
It was by way of total synthesis that the issues concerning the stereostructure of leiodermatolide (1) have recently been solved… Expand
2014
2014
Leiodermatolide is an antimitotic macrolide isolated from the marine sponge Leiodermatium sp. whose potentially novel tubulin… Expand
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Highly Cited
2011
Highly Cited
2011
Leiodermatolide is a structurally unique macrolide, isolated from the deep-water marine sponge Leiodermatium sp., which exhibits… Expand
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2011
2011
The macrocyclic core (2) of the marine macrolide leiodermatolide (1) has been synthesized in 19 steps through a convergent… Expand
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2011
2011
The synthesis of the 16-membered core structure of leiodermatolide 40 has been achieved in 26 linear steps starting from (R… Expand
2011
2011
The synthesis of three key fragments of the novel 16-membered macrolide leiodermatolide is described. The stereotetrad-containing… Expand