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leiodermatolide

 
National Institutes of Health

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Review
2017
Review
2017
This review highlights the various challenges overcome during our recent synthetic campaign towards (−)-leiodermatolide, a potent… Expand
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2017
2017
The C(1)-C(13) fragment of the antimitotic marine macrolide leiodermatolide is prepared in seven steps via hydrogenative and… Expand
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2017
2017
Two new analogues of the potent antitumor compound leiodermatolide, which we call leiodermatolides B and C, have been isolated… Expand
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2016
2016
Pancreatic cancer, the fourth leading cause of cancer death in the United States, has a negative prognosis because metastasis… Expand
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2016
2016
The macrocyclic core (35) of the marine natural product leiodermatolide (1) was synthesized from two key fragments, vinyl iodide… Expand
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2014
2014
It was by way of total synthesis that the issues concerning the stereostructure of leiodermatolide (1) have recently been solved… Expand
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2014
2014
Leiodermatolide is an antimitotic macrolide isolated from the marine sponge Leiodermatium sp. whose potentially novel tubulin… Expand
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2011
2011
The macrocyclic core (2) of the marine macrolide leiodermatolide (1) has been synthesized in 19 steps through a convergent… Expand
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2011
2011
The synthesis of the 16-membered core structure of leiodermatolide 40 has been achieved in 26 linear steps starting from (R… Expand
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2011
2011
Leiodermatolide is a structurally unique macrolide, isolated from the deep-water marine sponge Leiodermatium sp., which exhibits… Expand
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