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leiodermatolide

National Institutes of Health

Papers overview

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Review
2017
Review
2017
This review highlights the various challenges overcome during our recent synthetic campaign towards (−)-leiodermatolide, a potent… 
2017
2017
Two new analogues of the potent antitumor compound leiodermatolide, which we call leiodermatolides B and C, have been isolated… 
2017
2017
The C(1)–C(13) fragment of the antimitotic marine macrolide leiodermatolide is prepared in seven steps via hydrogenative and… 
2016
2016
Pancreatic cancer, the fourth leading cause of cancer death in the United States, has a negative prognosis because metastasis… 
2016
2016
The macrocyclic core (35) of the marine natural product leiodermatolide (1) was synthesized from two key fragments, vinyl iodide… 
Highly Cited
2014
Highly Cited
2014
It was by way of total synthesis that the issues concerning the stereostructure of leiodermatolide (1) have recently been solved… 
2014
2014
Leiodermatolide is an antimitotic macrolide isolated from the marine sponge Leiodermatium sp. whose potentially novel tubulin… 
Highly Cited
2011
Highly Cited
2011
The title compound strongly inhibits the cell proliferation of several cancer cell lines in vitro. 
2011
2011
The synthesis of the 16-membered core structure of leiodermatolide 40 has been achieved in 26 linear steps starting from (R… 
2011
2011
The macrocyclic core (2) of the marine macrolide leiodermatolide (1) has been synthesized in 19 steps through a convergent…