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latanoprost

Known as: Isopropyl (Z)-7-((1R,2R,3R,5S)-3,5-dihydroxy-2-((3R)-3-hydroxy-5-phenylpentyl)cyclopentyl)-5-heptenoate, latanoprost [Chemical/Ingredient], Propan-2-yl (5Z)-7-{(1R,2R,3R,5S)-3,5-dihydroxy-2-[(3R)-3-hydroxy-5-phenylpentyl]cyclopentyl}hept-5-enoate 
A prostaglandin F2alpha analogue and a prostanoid selective FP receptor agonist with an ocular hypertensive effect. Latanoprost increases uveoscleral… 
National Institutes of Health

Related topics

Related topics

10 relations

Broader (2)

Antihypertensive AgentsProstaglandins F, Synthetic
Glaucoma, Open-AngleProstaglandinsanalogs & derivativeslatanoprost / Timolol

Narrower (4)

PHXA41PhXA34Xalatanlatanoprost 0.05 MG/ML Ophthalmic Solution

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2014
Highly Cited
2014
A randomised, controlled comparison of latanoprostene bunod and latanoprost 0.005% in the treatment of ocular hypertension and open angle glaucoma: the VOYAGER study
Aim To assess the efficacy and safety of latanoprostene bunod (LBN) compared with latanoprost 0.005%, and to determine the… 
Highly Cited
2014
Highly Cited
2014
In vivo performance of a drug-eluting contact lens to treat glaucoma for a month.
Highly Cited
2008
Highly Cited
2008
The ocular surface of glaucoma patients treated over the long term expresses inflammatory markers related to both T-helper 1 and T-helper 2 pathways.
Review
2008
Review
2008
Conjunctival hyperaemia with the use of latanoprost versus other prostaglandin analogues in patients with ocular hypertension or glaucoma: a meta-analysis of randomised clinical trials
Aim: To conduct a meta-analysis of randomised clinical trials (RCTs) in order to evaluate the development of conjunctival… 
Highly Cited
2004
Highly Cited
2004
Conjunctival proinflammatory and proapoptotic effects of latanoprost and preserved and unpreserved timolol: an ex vivo and in vitro study.
PURPOSE To compare the toxicity of latanoprost and preserved and unpreserved timolol on conjunctival cells. Expression of… 
Highly Cited
2004
Highly Cited
2004
Patient persistency with topical ocular hypotensive therapy in a managed care population.
Review
2003
Review
2003
Interventions for angle-closure glaucoma: an evidence-based update.
Highly Cited
2001
Highly Cited
2001
Three-month comparison of bimatoprost and latanoprost in patients with glaucoma and ocular hypertension
A multicenter, randomized, investigator-masked, parallel-group trial compared bimatoprost and latanoprost for efficacy and safety… 
Review
2001
Review
2001
From PGF(2alpha)-isopropyl ester to latanoprost: a review of the development of xalatan: the Proctor Lecture.
From PGF(2alpha)-isopropyl ester to latanoprost: a review of the development of xalatan: the Proctor Lecture 
Review
1997
Review
1997
The color of the human eye: a review of morphologic correlates and of some conditions that affect iridial pigmentation.
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