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latanoprost

Known as: Isopropyl (Z)-7-((1R,2R,3R,5S)-3,5-dihydroxy-2-((3R)-3-hydroxy-5-phenylpentyl)cyclopentyl)-5-heptenoate, latanoprost [Chemical/Ingredient], Propan-2-yl (5Z)-7-{(1R,2R,3R,5S)-3,5-dihydroxy-2-[(3R)-3-hydroxy-5-phenylpentyl]cyclopentyl}hept-5-enoate 
A prostaglandin F2alpha analogue and a prostanoid selective FP receptor agonist with an ocular hypertensive effect. Latanoprost increases uveoscleral… 
National Institutes of Health

Related topics

Related topics

10 relations

Broader (2)

Antihypertensive AgentsProstaglandins F, Synthetic
Glaucoma, Open-AngleProstaglandinsanalogs & derivativeslatanoprost / Timolol

Narrower (4)

PHXA41PhXA34Xalatanlatanoprost 0.05 MG/ML Ophthalmic Solution

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2006
Highly Cited
2006
Comparison of invasive and non-invasive tonometry in the mouse.
2006
2006
The state of being noninferior.
Highly Cited
2005
Highly Cited
2005
Prostaglandin analogues and mouse intraocular pressure: effects of tafluprost, latanoprost, travoprost, and unoprostone, considering 24-hour variation.
PURPOSE To establish a mouse model for the pharmacological analysis of antiglaucoma drugs, considering the effect of variations… 
Highly Cited
2004
Highly Cited
2004
A 5-year, multicenter, open-label, safety study of adjunctive latanoprost therapy for glaucoma.
OBJECTIVE To evaluate the 5-year safety and efficacy of adjunctive 0.005% latanoprost once daily. METHODS Patients with primary… 
Highly Cited
1999
Highly Cited
1999
Cost considerations of medical therapy for glaucoma.
Highly Cited
1999
Highly Cited
1999
Intraocular Pressure-Lowering Effects of Latanoprost Monotherapy versus Latanoprost or Pilocarpine in Combination with Timolol
PurposeTo compare intraocular pressure (IOP) after adding either latanoprost or pilocarpine to timolol treatment or switching to… 
Highly Cited
1999
Highly Cited
1999
The effect of once-daily latanoprost on intraocular pressure and pulsatile ocular blood flow in normal tension glaucoma
Purpose To determine the effect of once-daily 0.005% latanoprost on intraocular pressure (IOP) and pulsatile ocular blood flow… 
Highly Cited
1997
Highly Cited
1997
Prostaglandin-induced iridial pigmentation in primates.
Review
1997
Review
1997
Structure-activity relationships and receptor profiles of some ocular hypotensive prostanoids.
Highly Cited
1994
Highly Cited
1994
Additive effect of latanoprost, a prostaglandin F2 alpha analogue, and timolol in patients with elevated intraocular pressure.
A randomised observer masked clinical study was conducted to assess the additive effect of latanoprost (13,14-dihydro-17-phenyl… 
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