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lansoprazole

Known as: 2-(((3-Methyl-4-(2,2,2-trifluoroethoxy)-2-pyridyl)methyl)sulfinyl)benzimidazole, Lansoprazole [Chemical/Ingredient], Lansoprazoles 
A substituted benzimidazole prodrug with selective and irreversible proton pump inhibitor activity. Lansoprazole prodrug is converted to an active… 
National Institutes of Health

Papers overview

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Highly Cited
2009
Highly Cited
2009
Background: Most proton pump inhibitors inhibit the bioactivation of clopidogrel to its active metabolite. The clinical… 
Highly Cited
2008
Highly Cited
2008
Prasugrel and clopidogrel, thienopyridine prodrugs, are each metabolized to an active metabolite that inhibits the platelet P2Y12… 
Highly Cited
2004
Highly Cited
2004
The human clearance of proton pump inhibitors (PPIs) of the substituted benzimidazole class is conducted primarily by the hepatic… 
Highly Cited
2003
Highly Cited
2003
OBJECTIVES:Proton pump inhibitors owe their clinical efficacy to their ability to suppress gastric acid production. The objective… 
Highly Cited
2002
Highly Cited
2002
BACKGROUND The role of gastric acid suppression in preventing the recurrence of ulcer complications after the eradication of… 
Highly Cited
2002
Highly Cited
2002
OBJECTIVES: Esomeprazole, the S isomer of omeprazole, has been shown to have higher healing rates of erosive esophagitis than… 
Highly Cited
2002
Highly Cited
2002
BACKGROUND Studies that report prevention of ulcer recurrence among long-term users of nonsteroidal anti-inflammatory drugs… 
Review
2002
Review
2002
Cytochrome P450 2C19 (CYP2C19) is the main (or partial) cause for large differences in the pharmacokinetics of a number of… 
Highly Cited
2001
Highly Cited
2001
Abstract. Proton pump inhibitors are a class of drugs which are widely prescribed for acid-related diseases. They are primarily…