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lansoprazole

Known as: 2-(((3-Methyl-4-(2,2,2-trifluoroethoxy)-2-pyridyl)methyl)sulfinyl)benzimidazole, Lansoprazole [Chemical/Ingredient], Lansoprazoles 
A substituted benzimidazole prodrug with selective and irreversible proton pump inhibitor activity. Lansoprazole prodrug is converted to an active… Expand
National Institutes of Health

Papers overview

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Highly Cited
2009
Highly Cited
2009
Background: Most proton pump inhibitors inhibit the bioactivation of clopidogrel to its active metabolite. The clinical… Expand
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Highly Cited
2009
Highly Cited
2009
OBJECTIVE To assess the efficacy and safety of lansoprazole in treating infants with symptoms attributed to gastroesophageal… Expand
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Highly Cited
2008
Highly Cited
2008
BACKGROUND The relation between Helicobacter pylori infection and gastric cancer has been proven in epidemiological studies and… Expand
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Highly Cited
2008
Highly Cited
2008
Prasugrel and clopidogrel, thienopyridine prodrugs, are each metabolized to an active metabolite that inhibits the platelet P2Y… Expand
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Highly Cited
2004
Highly Cited
2004
The human clearance of proton pump inhibitors (PPIs) of the substituted benzimidazole class is conducted primarily by the hepatic… Expand
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Highly Cited
2003
Highly Cited
2003
Gastric acid control with esomeprazole, lansoprazole, omeprazole, pantoprazole, and rabeprazole: a five-way crossover study 
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Highly Cited
2002
Highly Cited
2002
BACKGROUND The role of gastric acid suppression in preventing the recurrence of ulcer complications after the eradication of… Expand
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Highly Cited
2002
Highly Cited
2002
OBJECTIVES: Esomeprazole, the S isomer of omeprazole, has been shown to have higher healing rates of erosive esophagitis than… Expand
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Review
2002
Review
2002
Cytochrome P450 2C19 (CYP2C19) is the main (or partial) cause for large differences in the pharmacokinetics of a number of… Expand
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Highly Cited
2001
Highly Cited
2001
OBJECTIVE:Previous uncontrolled studies suggested a therapeutic benefit for treating gastroesophageal reflux disease (GERD) among… Expand
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