lansoprazole

Known as: 2-(((3-Methyl-4-(2,2,2-trifluoroethoxy)-2-pyridyl)methyl)sulfinyl)benzimidazole, Lansoprazole [Chemical/Ingredient], Lansoprazoles 
A substituted benzimidazole prodrug with selective and irreversible proton pump inhibitor activity. Lansoprazole prodrug is converted to an active… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1990-2018
05010019902018

Papers overview

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Highly Cited
2009
Highly Cited
2009
OBJECTIVE To assess the efficacy and safety of lansoprazole in treating infants with symptoms attributed to gastroesophageal… (More)
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Highly Cited
2008
Highly Cited
2008
Prasugrel and clopidogrel, thienopyridine prodrugs, are each metabolized to an active metabolite that inhibits the platelet P2Y… (More)
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Highly Cited
2005
Highly Cited
2005
BACKGROUND Difficult-to-control asthma has been associated with gastroesophageal acid reflux. Acid-suppressive treatment has been… (More)
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Highly Cited
2004
Highly Cited
2004
The human clearance of proton pump inhibitors (PPIs) of the substituted benzimidazole class is conducted primarily by the hepatic… (More)
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Highly Cited
2003
Highly Cited
2003
OBJECTIVES:Proton pump inhibitors owe their clinical efficacy to their ability to suppress gastric acid production. The objective… (More)
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Highly Cited
2002
Highly Cited
2002
BACKGROUND The role of gastric acid suppression in preventing the recurrence of ulcer complications after the eradication of… (More)
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Highly Cited
2002
Highly Cited
2002
OBJECTIVES: Esomeprazole, the S isomer of omeprazole, has been shown to have higher healing rates of erosive esophagitis than… (More)
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Highly Cited
2001
Highly Cited
2001
Proton pump inhibitors are a class of drugs which are widely prescribed for acid-related diseases. They are primarily metabolized… (More)
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Highly Cited
2001
Highly Cited
2001
OBJECTIVE:Previous uncontrolled studies suggested a therapeutic benefit for treating gastroesophageal reflux disease (GERD) among… (More)
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Highly Cited
1997
Highly Cited
1997
The human clearance of omeprazole and lansoprazole is conducted primarily by the hepatic cytochrome P450 (CYP) system. Efficacy… (More)
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