lactate biosynthetic process

Known as: lactate anabolism, lactate biosynthesis, lactate formation 
The chemical reactions and pathways resulting in the formation of lactate, the anion of lactic acid. [GOC:go_curators]
National Institutes of Health

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Highly Cited
2012
Highly Cited
2012
Metabolism of [U-13 C]glucose in human brain tumors in vivo.
Glioblastomas and brain metastases demonstrate avid uptake of 2-[(18) F]fluoro-2-deoxyglucose by positron emission tomography and… (More)
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Review
1998
Review
1998
Mammalian fuel utilization during sustained exercise.
The 'crossover' and 'lactate shuttle' concepts of substrate utilization in humans during exercise are extended to describe… (More)
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Highly Cited
1997
Highly Cited
1997
Administration of transgalacto-oligosaccharides increases fecal bifidobacteria and modifies colonic fermentation metabolism in healthy humans.
Transgalacto-oligosaccharides are a mixture of oligosaccharides consisting of glucose and galactose; they are not digested in the… (More)
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Highly Cited
1996
Highly Cited
1996
Activation of glycogen phosphorylase and glycogenolysis in rat skeletal muscle by AICAR--an activator of AMP-activated protein kinase.
We determined whether the cell permeable molecule AICAR, whose metabolite activates AMP-activated protein kinase (AMPK) in cells… (More)
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Highly Cited
1994
Highly Cited
1994
Nitric oxide-mediated inhibition of the mitochondrial respiratory chain in cultured astrocytes.
The Ca(2+)-independent form of nitric oxide synthase was induced in rat neonatal astrocytes in primary culture by incubation with… (More)
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Highly Cited
1994
Highly Cited
1994
Potent glycogenic effect of GLP-1(7–36)amide in rat skeletal muscle
GLP-1(7–36)amide is an intestinal posttranslational proglucagon product released mainly after carbohydrate ingestion, the glucose… (More)
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Highly Cited
1991
Highly Cited
1991
Influence of CO(2)-HCO(3) Levels and pH on Growth, Succinate Production, and Enzyme Activities of Anaerobiospirillum succiniciproducens.
Growth and succinate versus lactate production from glucose by Anaerobiospirillum succiniciproducens was regulated by the level… (More)
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Highly Cited
1987
Highly Cited
1987
Redox state and lactate accumulation in human skeletal muscle during dynamic exercise.
The relationship between the redox state and lactate accumulation in contracting human skeletal muscle was investigated. Ten men… (More)
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Highly Cited
1972
Highly Cited
1972
The activities of phosphorylase, hexokinase, phosphofructokinase, lactate dehydrogenase and the glycerol 3-phosphate dehydrogenases in muscles from vertebrates and invertebrates.
1. The maximum activities of hexokinase, phosphorylase and phosphofructokinase have been measured in extracts from a variety of… (More)
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Highly Cited
1958
Highly Cited
1958
Relationships of pyruvate and lactate during anaerobic metabolism. I. Effects of infusion of pyruvate or glucose and of hyperventilation.
During septic shock, muscle produces lactate by way of an exaggerated NaKYadenosine triphosphatase (ATPase)Ystimulated aerobic… (More)
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