Stimulation of Suicidal Erythrocyte Death by Benzethonium
@article{Lang2011StimulationOS, title={Stimulation of Suicidal Erythrocyte Death by Benzethonium}, author={E. Lang and K. Jilani and Christine Zelenak and Venkanna Pasham and Diwakar Bobbala and S. M. Qadri and F. Lang}, journal={Cellular Physiology and Biochemistry}, year={2011}, volume={28}, pages={347 - 354} }
Benzethonium, an antimicrobial surfactant widely used as preservative of pharmaceuticals, topical wound care product and oral disinfectant, triggers apoptosis of several cell types. The apoptosis is preceded and possibly triggered by mitochondrial depolarization. Even though lacking mitochondria, erythrocytes may similarly undergo suicidal cell death or eryptosis. Hallmarks of eryptosis include cell shrinkage and cell membrane scrambling with phosphatidylserine exposure at the cell surface… Expand
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