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knockin animal

National Institutes of Health

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Animals, Genetically Modified

Papers overview

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2019
2019
Generation of bicistronic reporter knockin mice for visualizing germ layers
Knockout mouse models are commonly used in developmental biology to investigate the functions of specific genes, and the… 
2018
2018
Abstract 450: Obesity favours leukemogenesis through enhanced preleukemic stem cell self renewal via polyunsaturated fatty acid-dependent ER stress relief
Obesity increases risk for multiple tumors, but impact on leukemia and its underlying molecular mechanism are poorly understood… 
2018
2018
JAK 2V 617 F promotes venous thrombosis through b 1 / b 2 integrin activation
JAK2-V617F–positive chronic myeloproliferative neoplasia (CMN) commonly displays dysfunction of integrins and adhesion molecules… 
Review
2013
Review
2013
Molecular mechanisms of renal and extrarenal manifestations caused by inactivation of the electrogenic Na+-HCO3− cotransporter NBCe1
The electrogenic Na+-HCO3− cotransporter NBCe1 plays an essential role in bicarbonate absorption from renal proximal tubules, but… 
2007
2007
Functional replacement of murine CXCR2 by its human homologue in the development of atherosclerosis in LDLR knockout mice.
The CXC chemokine receptor CXCR2 has been implicated in the pathogenesis of several chronic diseases including atherosclerosis… 
2007
2007
Analysis of antigen-stimulated B cell migration into germinal centers during the early stage of a T-dependent immune response.
2002
2002
T15-Idiotype-Negative B Cells Dominate the Phosphocholine Binding Cells in the Preimmune Repertoire of T15i Knockin Mice
T15i knockin (KI) mice express a H chain that is encoded by a rearranged T15 VDJ transgene which has been inserted into the JH… 
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