keratinocyte apoptotic process

Known as: keratinocyte apoptosis 
Any apoptotic process in a keratinocyte. A keratinocyte is an epidermal cell which synthesizes keratin and undergoes a characteristic change as it… (More)
National Institutes of Health

Papers overview

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2014
2014
Sharpin prevents skin inflammation by inhibiting TNFR1-induced keratinocyte apoptosis
Linear Ubiquitin chain Assembly Complex (LUBAC) is an E3 ligase complex that generates linear ubiquitin chains and is important… (More)
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Highly Cited
2010
Highly Cited
2010
IL-32 is expressed by human primary keratinocytes and modulates keratinocyte apoptosis in atopic dermatitis.
BACKGROUND Keratinocyte (KC) apoptosis is an important mechanism of eczema and spongiosis in patients with atopic dermatitis (AD… (More)
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2009
2009
Keratinocyte dysfunction in vitiligo epidermis: cytokine microenvironment and correlation to keratinocyte apoptosis.
Vitiligo is a skin disorder characterized by loss of functional melanocytes. Keratinocytes contribute to melanocyte homeostasis… (More)
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Highly Cited
2008
Highly Cited
2008
The Rac activator Tiam1 prevents keratinocyte apoptosis by controlling ROS-mediated ERK phosphorylation.
Tiam1 is a ubiquitously expressed activator of the small GTPase Rac. Previously, we found that Tiam1 knockout (KO) mice are… (More)
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Highly Cited
2006
Highly Cited
2006
Novel genomic effects of glucocorticoids in epidermal keratinocytes: inhibition of apoptosis, interferon-gamma pathway, and wound healing along with promotion of terminal differentiation.
Glucocorticoids (GCs) have a long history of use as therapeutic agents for numerous skin diseases. Surprisingly, their specific… (More)
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2003
2003
Epidermal COX-2 induction following ultraviolet irradiation: suggested mechanism for the role of COX-2 inhibition in photoprotection.
The cyclooxygenase isoforms, COX-1 and COX-2, are involved in the biosynthesis of prostaglandin E2, a major prostaglandin… (More)
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Highly Cited
2002
Highly Cited
2002
Skin inflammation during contact hypersensitivity is mediated by early recruitment of CD8+ T cytotoxic 1 cells inducing keratinocyte apoptosis.
Contact hypersensitivity (CHS) is a T cell-mediated, Ag-specific skin inflammation induced by skin exposure to haptens in… (More)
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2002
2002
NAD+-glycohydrolase acts as an intracellular toxin to enhance the extracellular survival of group A streptococci.
Group A streptococci (GAS) produce several secreted products that are thought to enhance pathogenicity by facilitating spread of… (More)
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Highly Cited
2000
Highly Cited
2000
T cell-mediated Fas-induced keratinocyte apoptosis plays a key pathogenetic role in eczematous dermatitis.
Clinical and histologic similarities between various eczematous disorders point to a common efferent pathway. We demonstrate here… (More)
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Highly Cited
2000
Highly Cited
2000
Inhibition of keratinocyte apoptosis by IL-15: a new parameter in the pathogenesis of psoriasis?
Keratinocytes (KC) are important source of and targets for several cytokines. Although KC express IL-15 mRNA, the functional… (More)
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