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itaconate

National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2018
Review
2018
Macrophages play a central role in innate immunity as the first line of defense against pathogen infection. Upon exposure to… 
Highly Cited
2017
Highly Cited
2017
Itaconic acid is an important metabolite produced by macrophages after stimulation with LPS. The role of itaconate in the… 
Highly Cited
2015
Highly Cited
2015
Upon stimulation with Th1 cytokines or bacterial lipopolysaccharides, resting macrophages shift their phenotype toward a pro… 
Highly Cited
2015
Highly Cited
2015
Itaconic acid is a bio-sourced dicarboxylic acid that carries a double bond; although several reports have dealt with the radical… 
Highly Cited
2014
Highly Cited
2014
Itaconate (methylenesuccinate) was recently identified as a mammalian metabolite whose production is substantially induced during… 
Highly Cited
2014
Highly Cited
2014
Interest in sustainable development has led to efforts to replace petrochemical-based monomers with biomass-based ones. Itaconic… 
Highly Cited
1995
Highly Cited
1995
Itaconate biosynthesis was studied in intact cells of high-yield (RC4') and low-yield (CM85J) strains of the fungus Aspergillus…