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isocupressic acid

Known as: 15-hydroxylabda-8(17),13-dien-19-oic acid 
National Institutes of Health

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3 relations

Broader (3)

Carboxylic AcidsDiterpenesTetrahydronaphthalenes

Papers overview

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2016
2016
A Concise Route to the Strongylophorines.
An efficient eight-step semisynthesis of strongylophorine-2 from the abundant building block isocupressic acid is reported. The… 
2004
2004
Isocupressic acid and new esters of it from the needles ofPinus sibirica
The acid fraction of an ethereal extract of the air-dry needles collected in March, 19S3~ was methylated with diazomethane and… 
2004
2004
Effects of the pine needle abortifacient , isocupressic acid , on bovine oocyte maturation and preimplantation embryo development
Isocupressic acid (ICA) [15-hydroxylabda-8 (17), 13E-dien-19-oic acid], a labdane diterpene acid, isolated from ponderosa pine… 
2003
2003
Development of enzyme-linked immunosorbent assays for isocupressic acid and serum metabolites of isocupressic acid.
The consumption of ponderosa pine (Pinus ponderosa), lodgepole pine (Pinus contorta), common juniper (Juniperus communis), and… 
2002
2002
Preparation of tetrahydroagathic acid: a serum metabolite of isocupressic acid, a cattle abortifacient in ponderosa pine.
Isocupressic acid (1) was used to synthetically prepare a mixture of (8S,13R,S)-labda-15,19-dioic acid (tetrahydroagathic acid… 
1999
1999
Abortifacient effects of a unique class of vasoactive lipids from Pinus ponderosa needles.
Pinus ponderosa needle (PN) ingestion by late pregnant cows results in decreased uterine blood flow, premature parturition, and… 
1998
1998
In vitro biotransformations of isocupressic acid by cow rumen preparations: formation of agathic and dihydroagathic acids.
Isocupressic acid [15-hydroxylabda-8(17),13E-dien-19-oic acid] (1) was incubated under anaerobic conditions for 48 h in an in… 
1998
1998
Pine needle consumption by cattle during winter in South Dakota.
Pregnant cattle that consume ponderosa pine (Pinus ponderosa (Lawson) needles often abort. The objectives of these studies were… 
Highly Cited
1994
Highly Cited
1994
Ponderosa Pine Needle-Induced Abortion in Beef Cattle: Identification of Isocupressic Acid as the Principal Active Compound
A crude acid fraction isolated from the needles of ponderosa pine (Pinus ponderosa Laws) induced abortions when fed to late-term… 
1991
1991
DITERPENOID ACIDS FROM THE LEAVES OF ARMAND PINE
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