intracellular lipid transport

The Steroidogenic Acute Regulatory Protein-related Lipid Transfer (START) domain is a ∼210 amino acid sequence that folds into an… Expand

Phosphatidylinositol (PI) is an inositol-containing phospholipid synthesized in the endoplasmic reticulum (ER). PI is a precursor… Expand

 

Stomatin, originally identified as a major protein of the human erythrocyte membrane, is widely expressed in various tissues… Expand

Intracellular lipid transport is one of the most fundamental processes in biology and is required for cellular replication… Expand

Niemann-Pick disease type C (NP-C) is an autosomal recessive disorder characterized by progressive neurological deterioration… Expand

Niemann-Pick disease type C (NPC) is a rare, neurovisceral lipid storage disorder caused by genetic defects in lipid transporting… Expand

Objective— Many cell types in atherosclerotic lesions are thought to have various biological abnormalities, such as impaired… Expand

The inter- and intramembrane transport of phospholipids, sphingolipids, and sterols involves the most fundamental processes of… Expand

Lipids fascinate cell biologists and biochemists because they can have profound effects on cell function. Encoded in these simple… Expand