interleukin-23

Known as: IL-23, Interleukin 23, Interleukin-23 [Chemical/Ingredient] 
A heterodimeric cytokine that plays a role in innate and adaptive immune responses. Interleukin-23 is comprised of a unique 19 kDa subunit and 40 kDa… (More)
National Institutes of Health

Papers overview

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Highly Cited
2010
Highly Cited
2010
Mutations in the IL23R gene are linked to inflammatory bowel disease susceptibility. Experimental models have shown that… (More)
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Highly Cited
2009
Highly Cited
2009
Lymphocyte recruitment and activation have been implicated in the progression of cerebral ischemia-reperfusion (I/R) injury, but… (More)
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Review
2008
Review
2008
Immune responses in the intestine are tightly regulated to ensure host protective immunity in the absence of immune pathology… (More)
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Highly Cited
2008
Highly Cited
2008
Intestinal macrophages play a central role in regulation of immune responses against commensal bacteria. In general, intestinal… (More)
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Highly Cited
2007
Highly Cited
2007
OBJECTIVE Recently, Th17 cells, a new subset of CD4+ T cells, emerged as major players in inflammation/autoimmunity. Maintenance… (More)
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Highly Cited
2007
Highly Cited
2007
Psoriasis is an inflammatory skin disorder that is inherited as a multifactorial trait. Genetic analyses have repeatedly… (More)
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Highly Cited
2006
Highly Cited
2006
Uncontrolled mucosal immunity in the gastrointestinal tract of humans results in chronic inflammatory bowel disease (IBD), such… (More)
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Highly Cited
2006
Highly Cited
2006
Inflammatory bowel disease (IBD) is a chronic inflammatory disorder of the gastrointestinal tract involving aberrant activation… (More)
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Highly Cited
2006
Highly Cited
2006
The inflammatory bowel diseases Crohn's disease and ulcerative colitis are common, chronic disorders that cause abdominal pain… (More)
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Highly Cited
2006
Highly Cited
2006
The CD40-CD154 pathway is important in the pathogenesis of inflammatory bowel disease. Here we show that injection of an… (More)
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