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interleukin-23

Known as: IL-23, Interleukin 23, Interleukin-23 [Chemical/Ingredient] 
A heterodimeric cytokine that plays a role in innate and adaptive immune responses. Interleukin-23 is comprised of a unique 19 kDa subunit and 40 kDa… 
National Institutes of Health

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Related topics

12 relations
IL23A geneIL23A protein, humanIL23A wt AlleleIn Blood

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2013
2013
IL‐23 protection against Plasmodium berghei infection in mice is partially dependent on IL‐17 from macrophages
Although IL‐12 is believed to contribute to protective immune responses, the role played by IL‐23 (a member of the IL‐12 family… 
2013
2013
Interleukin 23 regulates proliferation of lung cancer cells in a concentration-dependent way in association with the interleukin-23 receptor.
A proinflammatory cytokine, interleukin 23 (IL-23), plays a role in tumor progression by inducing inflammation in the tumor… 
2011
2011
Regulation of the development of acute hepatitis by IL‐23 through IL‐22 and IL‐17 production
IL‐23 plays a critical role in the expansion of highly proinflammatory Th17 cells secreting IL‐17 and IL‐22. Recently, we… 
2010
2010
Administration of IL-23 engages innate and adaptive immune mechanisms during fungal infection.
IL-23 is a key cytokine in promotion of chronic inflammation. Here, we address if its pro-inflammatory potential can be harnessed… 
2010
2010
Diamino-1,2,4-triazole derivatives are selective inhibitors of TYK2 and JAK1 over JAK2 and JAK3.
2009
2009
Early regulators in abortion and implications for a preeclampsia model.
2007
2007
Analysis of interleukin-23 receptor (IL23R) gene polymorphisms in systemic lupus erythematosus.
The aim of this study was to evaluate the association between systemic lupus erythematosus (SLE) and polymorphisms in the… 
Review
2006
Review
2006
Rationale and safety of anti-interleukin-23 and anti-interleukin-17A therapy
Purpose of review Interleukin-12 is a heterodimeric cytokine and an important mediator of the cellular immune response. The… 
Review
2006
Review
2006
Regulation of innate and adaptive immune responses by the related cytokines IL-12, IL-23, and IL-27
Abstract.The functional characterization and subsequent purification of T cell growth factor/interleukin (IL)-2 in the early… 
2006
2006
The many roads to inflammatory bowel diseases.
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