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IL23A wt Allele

Known as: Interleukin-Six, G-CSF Related Factor Gene, SGRF, IL-23 
Human IL23A wild-type allele is located in the vicinity of 12q13.2 and is approximately 2 kb in length. This allele, which encodes interleukin-23… 
National Institutes of Health

Related topics

Related topics

11 relations
12q13Cell Proliferation Regulatory ProcessCytokine Receptor BindingCytokine Signaling

Broader (1)

IL23A gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2014
2014
Elevated Proinflammatory Cytokine IL-17A in the Adjacent Tissues Along the Adenoma-Carcinoma Sequence
Considerable evidence has suggested that chronic inflammation is a causative factor in the development of human colorectal cancer… 
2013
2013
IL‐23 protection against Plasmodium berghei infection in mice is partially dependent on IL‐17 from macrophages
Although IL‐12 is believed to contribute to protective immune responses, the role played by IL‐23 (a member of the IL‐12 family… 
2012
2012
IFN-γ induced by IL-12 administration prevents diabetes by inhibiting pathogenic IL-17 production in NOD mice.
2011
2011
Regulation of the development of acute hepatitis by IL‐23 through IL‐22 and IL‐17 production
IL‐23 plays a critical role in the expansion of highly proinflammatory Th17 cells secreting IL‐17 and IL‐22. Recently, we… 
2011
2011
Novel approach for interleukin‐23 up‐regulation in human dendritic cells and the impact on T helper type 17 generation
Interleukin‐23 (IL‐23) is important for T helper type 17 (Th17) responses and strategies to regulate IL‐23 in human dendritic… 
2010
2010
Raised concentration of soluble form of vascular endothelial cadherin and IL-23 in sera of patients with Behçet’s disease
Behçet’s disease (BD) is a chronic multisystem vasculitis disease that can affect any organ and usually is combined with… 
2010
2010
Interleukin-23 production in dendritic cells is negatively regulated by protein phosphatase 2A
IL-12 and IL-23 are produced by activated antigen-presenting cells but the two induce distinct immune responses by promoting Th1… 
2008
2008
Differences in the inducible gene expression and protein production of IL-12p40, IL-12p70 and IL-23: involvement of p38 and JNK kinase pathways.
Highly Cited
2006
Highly Cited
2006
Interleukin-23 Restores Immunity to Mycobacterium tuberculosis Infection in IL-12p40-Deficient Mice and Is Not Required for the Development of IL-17-Secreting T Cell Responses1
Host control of Mycobacterium tuberculosis is dependent on the activation of CD4+ T cells secreting IFN-γ and their recruitment… 
2006
2006
The use of Th1 cytokines, IL-12 and IL-23, to modulate the immune response raised to a DNA vaccine delivered by gene gun.
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