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interleukin-15 receptor activity

Known as: IL-15 receptor activity, IL-15R 
Combining with interleukin-15 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. [GOC:jl… 
National Institutes of Health

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interleukin-15 binding activity
interleukin-15 receptor

Papers overview

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2018
2018
Role of Common γ-Chain Cytokines in Lung Interleukin-22 Regulation after Acute Exposure to Aspergillus fumigatus
Humans are constantly exposed to the opportunistic mold Aspergillus fumigatus, and disease caused by this pathogen is often… 
2008
2008
The IL-15 receptor chain cytoplasmic domain is critical for normal IL-15R function but is not required for trans-presentation
IL-15 is critical for natural killer (NK)–cell development and function and for memory CD8 T-cell homeostasis. The IL-15 receptor… 
2007
2007
IL-15 in the life and death of lymphocytes: Implications for cancer therapy and vaccine design
SY08-02 Interleukin-2 and Interleukin-15 have pivotal roles in the control of the life and death of lymphocytes. Although their… 
2006
2006
Il-15r Beta / Il15r alpha sushi domain of the gamma as selective and potent enhancer of il-15 activity via and hyper agonists, (il15r alpha sushi -Il15) fusion protein
The present invention is to stimulate IL-15R beta / gamma signaling pathway, thereby inducing and / or stimulating the activation… 
2003
2003
Mast Cells Express Novel Functional IL-15 Receptor α Isoforms1
Mast cells previously have been reported to be regulated by IL-15 and to express a distinct IL-15R, termed IL-15RX. To further… 
2002
2002
Étude des fonctions de l'interleukine-15 et de la chaîne IL-15R alpha dans les cellules hématopoi͏̈étiques et non-hématopoi͏̈étiques
Highly Cited
2000
Highly Cited
2000
The Pleiotropic Functions of Interleukin 15
Since its in 1994, IL-15 has been studied in the context of its structural cousin, IL-2 (1). Early biochemical and in vitro… 
1999
1999
IL-15/IL-15R alpha intracellular trafficking in human cells and protection from apoptosis.
IL-15 is an immunostimulatory cytokine sharing with IL-2 the IL-2R beta gamma complex. In vivo, IL-15 detection in synovial… 
Highly Cited
1998
Highly Cited
1998
Interleukin-15 (IL-15) can replace the IL-2 signal in IL-2-dependent adult T-cell leukemia (ATL) cell lines: expression of IL-15 receptor alpha on ATL cells.
Interleukin-15 receptor (IL-15R) and IL-2R have the same beta and gamma chains, but IL-15R has a specific alpha chain distinct… 
Highly Cited
1997
Highly Cited
1997
Role for IL-15/IL-15 receptor beta-chain in natural killer 1.1+ T cell receptor-alpha beta+ cell development.
Mouse TCR alphabeta+ cells expressing NKR-P1 (NK1+ T cells in the C57BL/6 strain) are classified as a unique subset that require… 
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