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interleukin-12 complex

Known as: interleukin-12 complex location, IL-12 complex, p40 
A protein complex that is composed of an interleukin-12 alpha (p35, product of the IL12A gene) and an interleukin-12 beta subunit (p40, product of… Expand
National Institutes of Health

Papers overview

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2013
2013
OBJECTIVE To ascertain whether AS-associated polymorphisms of ERAP1, IL23R and IL12B genes associate with subphenotypes of PsA… Expand
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2012
2012
Of eight leprosy susceptibility loci identified by genome-wide association studies, five have been implicated in Crohn disease… Expand
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2011
2011
To investigate the association between the potentially functional polymorphisms in IL12A and IL12B, HBV infection and risk of… Expand
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Highly Cited
2009
Highly Cited
2009
BACKGROUND Primary biliary cirrhosis is a chronic granulomatous cholangitis, characteristically associated with antimitochondrial… Expand
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Highly Cited
2008
Highly Cited
2008
Psoriasis is a common inflammatory and hyperproliferative skin disease with a multifactorial genetic basis. A recent study… Expand
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2008
2008
OBJECTIVE The aim of this study was to investigate whether IL12B polymorphisms might be associated with increased risk and… Expand
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Highly Cited
2007
Highly Cited
2007
We performed a multitiered, case-control association study of psoriasis in three independent sample sets of white North American… Expand
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Highly Cited
2004
Highly Cited
2004
Identifying regions of the human genome that have been targets of natural selection will provide important insights into human… Expand
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2004
2004
The IL12B gene on chromosome 5q31-33 encodes the p40 subunit of interleukin 12, an immunomodulatory cytokine. To test the… Expand
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2004
2004
Type 1 (insulin dependent) diabetes mellitus (T1DM) [MIM 222100] is an autoimmune disease with both genetic and environmental… Expand
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