IL12B protein, human

Known as: IL-12p40, Cytotoxic Lymphocyte Maturation Factor 2, IL12-p40 
Interleukin-12 subunit beta (328 aa, ~37 kDa) is encoded by the human IL12B gene. This protein is involved in the growth of both natural killer cells… (More)

Topic mentions per year

Topic mentions per year

1993-2017
05010019932017

Papers overview

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Highly Cited
2012
Highly Cited
2012
Microbial penetration of the intestinal epithelial barrier triggers inflammatory responses that include induction of the… (More)
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Highly Cited
2012
Highly Cited
2012
Both microglia, the resident myeloid cells of the CNS parenchyma, and infiltrating blood-derived macrophages participate in… (More)
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Highly Cited
2007
Highly Cited
2007
Vitamin D deficiency is associated with susceptibility to tuberculosis, and its biologically active metabolite, 1alpha,25… (More)
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Highly Cited
2005
Highly Cited
2005
IL-12 is a potent inducer of IFN-gamma production and promotes a protective cell-mediated immune response after Mycobacterium… (More)
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Highly Cited
2003
Highly Cited
2003
Toll-like receptors (TLR) recognize microbial and viral patterns and activate dendritic cells (DC). TLR distribution among human… (More)
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Highly Cited
2001
Highly Cited
2001
Type 1 diabetes (T1D; or insulin-dependent diabetes mellitus, IDDM) is an autoimmune disease with both genetic and environmental… (More)
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Highly Cited
2001
Highly Cited
2001
Interleukin-12 p70 (IL-12p70) heterodimer, composed of p35 and p40 subunits, is a major Th1-driving cytokine, promoting cell… (More)
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Highly Cited
2000
Highly Cited
2000
A novel sequence discovered in a computational screen appears distantly related to the p35 subunit of IL-12. This factor, which… (More)
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Highly Cited
1998
Highly Cited
1998
To analyze the roles of interleukin-12 (IL-12) and the IL-12-dependent Th1 response in resistance to Cryptococcus neoformans, we… (More)
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Highly Cited
1995
Highly Cited
1995
Pathogenic bacteria that penetrate the intestinal epithelial barrier stimulate an inflammatory response in the adjacent… (More)
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