FAQ

IL12A gene

Known as: NKSF1, CLMF, Interleukin 12A (Natural Killer Cell Stimulatory Factor 1, Cytotoxic Lymphocyte Maturation Factor 1, P35) Gene 
This gene plays a role in immunity/defense via the stimulation of both T cells and natural killer cells. It is also involved in cell differentiation.
National Institutes of Health

Topic mentions per year

Topic mentions per year

1994-2017
024619942017

Related topics

Related topics

15 relations
Cell Differentiation processCell Proliferation Regulatory ProcessCellular ImmunityCytokine Receptor Binding
(More)

Narrower (1)

IL12A wt Allele

Related mentions per year

Related mentions per year

1938-2018
19401960198020002020
IL12A gene
Cell Differentiation process
T-Cell Activation
Cellular Immunity
Recombinant Interleukin-12
Intercellular Communication Process

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2015
2015
Association between polymorphisms of interleukin 12 and rheumatoid arthritis associated biomarkers in a Chinese population.
INTRODUCTION The aim of the present study was to examine the association between polymorphisms of interleukin 12 (IL-12) and… (More)
Is this relevant?
2014
2014
Association of IL-12A and IL-12B polymorphisms with Alzheimer's disease susceptibility in a Han Chinese population.
As a pro-inflammatory cytokine belonging to the interleukin (IL)-1 family, IL-12 is recently found to be involved in the… (More)
Is this relevant?
2012
2012
Associations between polymorphisms in IL-12A, IL-12B, IL-12Rβ1, IL-27 gene and serum levels of IL-12p40, IL-27p28 with esophageal cancer
The aim of this study was to investigate whether IL-12A, IL-12B, IL-12Rβ1, and IL-27 gene polymorphisms and serum levels of IL-12… (More)
  • table 1
  • table 2
  • table 3
Is this relevant?
2012
2012
Gene-gene interactions between interleukin-12A and interleukin-12B with the risk of brain tumor.
Emerging evidence from preclinical and clinical studies has shown that interleukin-12 (IL-12) has some effectiveness against… (More)
Is this relevant?
2012
2012
Gene expression changes in human islets exposed to type 1 diabetic serum.
A major obstacle to the success of islet cell transplantation as a standard treatment for labile type 1 diabetes mellitus is the… (More)
  • figure 1
  • figure 2
  • table 1
  • figure 3
  • figure 4
Is this relevant?
2011
2011
Association of single nucleotide polymorphisms in interleukin 12 (IL-12A and -B) with asthma in a Chinese population.
Increasing evidence has indicated that genetic variants may contribute to immune dysregulation and susceptibility to… (More)
Is this relevant?
2011
2011
The influence of methotrexate on the gene expression of the pro-inflammatory cytokine IL-12A in the therapy of rheumatoid arthritis.
OBJECTIVES Methotrexate (MTX) is a cornerstone in the treatment of rheumatoid arthritis (RA). Among its anti-proliferative… (More)
Is this relevant?
2005
2005
Polymorphisms in cytokine and cellular adhesion molecule genes and susceptibility to hematotoxicity among workers exposed to benzene.
Benzene is a recognized hematotoxin and leukemogen but its mechanism of action and the role of genetic susceptibility are still… (More)
  • table 1
  • table 2
  • table 3
  • table 4
  • table 4
Is this relevant?
2000
2000
Novel amplification unit at chromosome 3q25-q27 in human prostate cancer.
BACKGROUND In prostate carcinoma, amplification of the genes c-MYC, Her2/NEU, and the androgen receptor gene has been documented… (More)
Is this relevant?
1994
1994
Molecular mapping of uncharacteristically small 5q deletions in two patients with the 5q- syndrome: delineation of the critical region on 5q and identification of a 5q- breakpoint.
Molecular mapping techniques have defined the region of gene loss in two patients with the 5q- syndrome and uncharacteristically… (More)
Is this relevant?