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interleukin-10 receptor

Known as: IL-10 Receptors, IL 10 Receptor, Interleukin 10 Receptors 
Cell surface receptors for INTERLEUKIN-10. They exist as a tetramer of two alpha chains (INTERLEUKIN-10 RECEPTOR ALPHA CHAIN) and two beta chains… 
National Institutes of Health

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IL10RA geneIn Bloodagonistsantagonists & inhibitors

Papers overview

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Review
2014
Review
2014
Interleukin 10 receptor signaling: master regulator of intestinal mucosal homeostasis in mice and humans.
Review
2014
Review
2014
Taste bud homeostasis in health, disease, and aging.
The mammalian taste bud is an onion-shaped epithelial structure with 50-100 tightly packed cells, including taste receptor cells… 
Highly Cited
2011
Highly Cited
2011
CD 4 + T cell help and innate-derived IL-27 induce Blimp-1-dependent IL-10 production by antiviral CTLs
IL-10 is an important anti-inflammatory cytokine that can suppress both innate and adaptive immune responses to infectious agents… 
Highly Cited
2006
Highly Cited
2006
Gene polymorphisms in Toll-like receptors, interleukin-10, and interleukin-10 receptor alpha and lymphoma risk
Interactions between environment and immune system play an essential role in the aetiology of immunopathologies, including… 
Highly Cited
2006
Highly Cited
2006
Cytokine Responses in Gnotobiotic Pigs after Infection with Virulent or Attenuated Human Rotavirus
ABSTRACT To understand the role of cytokines during rotavirus infection, we assessed the kinetics of tumor necrosis factor alpha… 
Highly Cited
2004
Highly Cited
2004
Human Cytomegalovirus Interleukin-10 Downregulates Metalloproteinase Activity and Impairs Endothelial Cell Migration and Placental Cytotrophoblast Invasiveness In Vitro
ABSTRACT At the uterine-placental interface, fetal cytotrophoblasts invade the decidua, breach maternal blood vessels, and form… 
Highly Cited
2002
Highly Cited
2002
Expression and regulation of interleukin‐10 and interleukin‐10 receptor in rat astroglial and microglial cells
Activated glial cells crucially contribute to brain inflammatory responses. Interleukin‐10 (IL‐10) is an important modulator of… 
Highly Cited
2001
Highly Cited
2001
Interleukin-10 and interleukin-10 receptor in human osteoarthritic and healthy chondrocytes.
OBJECTIVE To evaluate the expression of interleukin-10 (IL-10) and interleukin-10 receptor (IL-10R) on chondrocytes from healthy… 
Highly Cited
1997
Highly Cited
1997
Identification and functional characterization of a second chain of the interleukin‐10 receptor complex
Interleukin‐10 (IL‐10) is a pleiotropic cytokine which signals through a specific cell surface receptor complex. Only one chain… 
Highly Cited
1996
Highly Cited
1996
Stat3 Recruitment by Two Distinct Ligand-induced, Tyrosine-phosphorylated Docking Sites in the Interleukin-10 Receptor Intracellular Domain*
Recent work has shown that IL-10 induces activation of the JAK-STAT signaling pathway. To define the mechanism underlying signal… 
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