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interleukin-1 receptor antagonist activity

Known as: IL-1ra 
Blocks the binding of interleukin-1 to the interleukin-1 receptor complex. [GOC:ebc]
National Institutes of Health

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4 relations
IL1RN wt AlleleInterleukin 1 Receptor Antagonist ProteinInterleukin-1 Receptor Antagonist [EPC]anakinra

Papers overview

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2012
2012
Estradiol, tamoxifen, and flaxseed alter IL-1β and IL-1Ra levels in normal human breast tissue in vivo.
INTRODUCTION Sex steroid exposure increases the risk of breast cancer by unclear mechanisms. Diet modifications may be one breast… 
Review
2010
Review
2010
Role of interleukin polymorphisms in gastric cancer: "Pros and cons".
Helicobacter pylori (H. pylori) infection is the leading cause of gastric cancer worldwide. Infection with this bacterium causes… 
2009
2009
Gene polymorphisms of TNF-α−308 (G/A), IL-10−1082 (G/A), IL-6−174 (G/C) and IL-1Ra (VNTR) in Egyptian cases with type 1 diabetes mellitus
Background. Type 1 diabetes (T1D) is a genetically conditioned autoimmune disease in which cytokines play an important role… 
Highly Cited
2000
Highly Cited
2000
Smoking and GCF levels of IL-1beta and IL-1ra in periodontal disease.
AIMS GCF levels of the cytokine IL-1beta and its receptor antagonist IL-1ra were analyzed with respect to smoking in patients… 
1999
1999
Inhibitory Effects of Endotoxin on LH Secretion in the Ovariectomized Monkey Are Prevented by Naloxone but Not by an Interleukin-1 Receptor Antagonist
Endotoxin (lipopolysaccharides, LPS), the pathogenic moiety of gram-negative bacteria, is a well-known trigger for the central… 
1998
1998
IL-1ra versus IL-1 Levels in Prostatic Fluid from Prostatitis Patients
Recent papers reported that the balance between the production of IL-1ra and IL-1 probably influences the regulation of host… 
1997
1997
Differences in responses of interleukin‐1 and tumor necrosis factor α production and secretion to cyclosporin‐A and ultraviolet B‐irradiation by normal and transformed keratinocyte cultures
Abstract Among epidermal cytokines, IL‐1 and TNFα are involved in inflammatory skin reactions and suspected of modulation by… 
1997
1997
Increased interleukin-1 and interleukin-1 receptor antagonist levels in cervical mucus in the ovulatory phase in comparison with the follicular phase.
Interleukin-1 (IL-1) receptor antagonist (IL-1ra) levels in the cervical mucus of women in the ovulatory phase are significantly… 
1995
1995
Differential effects of interleukin-1 receptor antagonist in cytokine- and endotoxin-treated rats.
Previous studies have demonstrated that the administration of the cytokines, interleukin-1 (IL-1) and tumor necrosis factor (TNF… 
1991
1991
Inhibition by interleukin 1 receptor antagonist of in vivo activities of interleukin 1 in mice.
A polypeptide homologous to IL-1, with antagonistic activity (IL-1ra), has recently been described. Given the pleiotropic… 
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