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inner ear development

The process whose specific outcome is the progression of the inner ear over time, from its formation to the mature structure. [GOC:sr]
National Institutes of Health

Related topics

Related topics

6 relations

Narrower (5)

cochlea developmentinner ear morphogenesisinner ear receptor cell differentiationotolith development

Broader (1)

ear development

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2015
Highly Cited
2015
Gene Expression by Mouse Inner Ear Hair Cells during Development
Hair cells of the inner ear are essential for hearing and balance. As a consequence, pathogenic variants in genes specifically… 
Highly Cited
2013
Highly Cited
2013
Generation of inner ear sensory epithelia from pluripotent stem cells in 3D culture
The inner ear contains sensory epithelia that detect head movements, gravity and sound. It is unclear how to develop these… 
Review
2012
Review
2012
Molecular mechanisms of inner ear development.
The inner ear is a structurally complex vertebrate organ built to encode sound, motion, and orientation in space. Given its… 
Highly Cited
2007
Highly Cited
2007
Cross-regulation of Ngn1 and Math1 coordinates the production of neurons and sensory hair cells during inner ear development
Temporal and spatial coordination of multiple cell fate decisions is essential for proper organogenesis. Here, we define gene… 
Highly Cited
2005
Highly Cited
2005
Two contrasting roles for Notch activity in chick inner ear development: specification of prosensory patches and lateral inhibition of hair-cell differentiation
Lateral inhibition mediated by Notch is thought to generate the mosaic of hair cells and supporting cells in the inner ear, but… 
Review
2004
Review
2004
From placode to polarization: new tunes in inner ear development
The highly orchestrated processes that generate the vertebrate inner ear from the otic placode provide an excellent and… 
Highly Cited
2002
Highly Cited
2002
The role of Math1 in inner ear development: Uncoupling the establishment of the sensory primordium from hair cell fate determination.
During embryonic development of the inner ear, the sensory primordium that gives rise to the organ of Corti from within the… 
Highly Cited
2000
Highly Cited
2000
Identification of synergistic signals initiating inner ear development.
Tissue manipulation experiments in amphibians more than 50 years ago showed that induction of the inner ear requires two signals… 
Highly Cited
1999
Highly Cited
1999
Expression pattern of the mouse ortholog of the Pendred's syndrome gene (Pds) suggests a key role for pendrin in the inner ear.
Pendred's syndrome is an autosomal-recessive disorder characterized by deafness and goiter. After our recent identification of… 
Highly Cited
1996
Highly Cited
1996
Early ear development in the embryo of the Zebrafish, Danio rerio
The zebrafish provides an important model for vertebrate inner ear development. The otic placode becomes visible at ∼16 hours (at… 
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