inner ear development

Inner ear development requires coordinated transformation of a uniform sheet of cells into a labyrinth with multiple cell types… (More)

A cascade of transcription factors is believed to regulate the coordinate differentiation of primordial inner ear cells into the… (More)

Members of the Dlx gene family play essential roles in the development of the zebrafish and mouse inner ear, but little is known… (More)

The paired box transcription factor, Pax2, is important for cochlear development in the mouse inner ear. Two mutant alleles of… (More)

Members of the fibroblast growth factor (FGF) gene family control formation of the body plan and organogenesis in vertebrates… (More)

TBX1 is thought to be a critical gene in the pathogenesis of del22q11/DiGeorge syndrome (DGS). Morphological abnormalities of the… (More)

During embryonic development of the inner ear, the sensory primordium that gives rise to the organ of Corti from within the… (More)

Tissue manipulation experiments in amphibians more than 50 years ago showed that induction of the inner ear requires two signals… (More)

The zebrafish provides an important model for vertebrate inner ear development. The otic placode becomes visible at approximately… (More)

Fibroblast growth factor receptor 3 (Fgfr3) is a tyrosine kinase receptor expressed in developing bone, cochlea, brain and spinal… (More)