FAQ

inhibition of serotonin uptake

Known as: inhibition of 5HT uptake, inhibition of serotonin import, inhibition of 5-HT uptake 
Any process that prevents the activation of the directed movement of serotonin into a cell. [GOC:ai]
National Institutes of Health

Topic mentions per year

Topic mentions per year

1970-2018
024619702018

Papers overview

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Highly Cited
1997
Highly Cited
1997
Carrier-dependent and Ca(2+)-dependent 5-HT and dopamine release induced by (+)-amphetamine, 3,4-methylendioxymethamphetamine, p-chloroamphetamine and (+)-fenfluramine.
1. The mechanism underlying 5-hydroxytryptamine (5-HT) and/or dopamine release induced by (+)-amphetamine ((+)-Amph), 3,4… (More)
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1993
1993
Norfluoxetine Enantiomers as Inhibitors of Serotonin Uptake in Rat Brain
Like fluoxetine, the N-demethylated metabolite norfluoxetine exists in R- and S-enantiomeric forms. S-Norfluoxetine inhibited… (More)
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1992
1992
Serotonin as a regulator of craniofacial morphogenesis: site specific malformations following exposure to serotonin uptake inhibitors.
During craniofacial development in the mouse embryo (days 9-12 of gestation; plug day = day 1), transient expression of serotonin… (More)
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Highly Cited
1992
Highly Cited
1992
The pharmacological effect of citalopram resides in the (S)-(+)-enantiomer
The enantiomers of citalopram and N-demethylcitalopram have been investigated. Based on the inhibition of 5-HT uptake in vitro… (More)
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Highly Cited
1991
Highly Cited
1991
Dual effect of serotonin on growth of bovine pulmonary artery smooth muscle cells in culture.
We have previously reported that serotonin (5-hydroxytryptamine [5HT]) alters cultured bovine pulmonary artery smooth muscle cell… (More)
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1991
1991
Differential effects of clomipramine given locally or systemically on extracellular 5-hydroxytryptamine in raphe nuclei and frontal cortex. An in vivo brain microdialysis study.
The antidepressant drug clomipramine (CIM) blocks 5-hydroxytryptamine (5-HT) uptake in vitro. Electrophysiological studies have… (More)
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1985
1985
Combined inhibition of serotonin uptake and oxidative deamination attenuates audiogenic seizures in DBA/2J mice.
We previously reported that 6-methoxy-1,2,3,4-tetrahydro-beta-carboline (6-MeO-THBC) attenuated audiogenic seizures (AGS) in 21… (More)
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1985
1985
Relationship between clinical effects, serum drug concentration and serotonin uptake inhibition in depressed patients treated with citalopram
Three dose levels (5, 25, and 50 mg once daily) of the selective serotonin uptake inhibitor citalopram were compared in a four… (More)
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1977
1977
Neurochemical characterization of a new potent and selective serotonin uptake inhibitor: Lu 10-171
The neurochemical characteristics of a new bicyclic phthalane derivative — Lu 10-171 [1-(3-(dimethylamino)propyl)-1-(p… (More)
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1976
1976
Sex specific differences in chlorimipramine inhibition of serotonin uptake in human platelets.
The uptake of 14C-serotonin in platelet-rich plasma was similar in clinically healthy men and women. Serotonin uptake inhibition… (More)
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