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indoleamine 2,3-dioxygenase activity

Known as: IDO 
Catalysis of the reaction: tryptophan + O2 = N-formylkynurenine. The product of the reaction depends on the substrate; D-tryptophan produces N-formyl… 
National Institutes of Health

Papers overview

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2011
2011
Dendritic cells (DC) are professional antigen-presenting cells (APCs) that modulate the outcome of the immune response toward… 
2010
2010
The balance between immunity and tolerance in the endometrium is governed by dynamic interactions of UEC and immune cells… 
2009
2009
Previous cancer vaccination approaches have shown some efficiency in generating measurable immune responses, but they have rarely… 
2007
2007
Blockade of CD40-CD40 ligand (CD40L) costimulation has been shown to synergize with that of CTLA4/CD28-B7 to promote transplant… 
Review
2005
Review
2005
Activation of the tryptophan catabolizing enzyme indoleamine 2,3-dioxygenase (IDO) in cancer cells facilitates immune escape. A… 
Review
1996
Review
1996
The following is our current working hypothesis concerning the biological significance of IDO induction. When tissues are invaded…