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indole-3-carbinol

Known as: indole 3 carbinol, 1H-indole-3-methanol, I3C 
A naturally occurring, orally available cleavage product of the glucosinolate glucobrassicanin, a natural compound present in a wide variety of plant… 
National Institutes of Health

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Broader (2)

Anticarcinogenic AgentsIndoles

Papers overview

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Highly Cited
2006
Highly Cited
2006
3,3'-Diindolylmethane downregulates pro-survival pathway in hormone independent prostate cancer.
Highly Cited
2003
Highly Cited
2003
A new indole-3-carbinol tetrameric derivative inhibits cyclin-dependent kinase 6 expression, and induces G1 cell cycle arrest in both estrogen-dependent and estrogen-independent breast cancer cell…
Indole-3-carbinol (I3C), autolysis product of glucosinolates present in cruciferous vegetables, has been indicated as a promising… 
Highly Cited
1996
Highly Cited
1996
Solid‐state NMR studies of the prion protein H1 fragment
Conformational changes in the prion protein (PrP) seem to be responsible for prion diseases. We have used conformation‐dependent… 
Review
1994
Review
1994
Strategy and planning for chemopreventive drug development: Clinical development plans
At the National Cancer Institute, Division of Cancer Prevention and Control, the Chemoprevention Branch and Agent Development… 
Highly Cited
1991
Highly Cited
1991
Promotion of aflatoxin B1 carcinogenesis by the natural tumor modulator indole-3-carbinol: influence of dose, duration, and intermittent exposure on indole-3-carbinol promotional potency.
Indole-3-carbinol (13C), a secondary metabolite from cruciferous vegetables, inhibits aflatoxin B1 (AFB1) hepatocarcinogenesis in… 
Highly Cited
1991
Highly Cited
1991
Homotropenylium Cation: Structure, Stability, and Magnetic Properties
The equilibrium geometry of the homotropenylium cation (1) and its planar form (5) have been calculated at the MP2/6-31G(d) level… 
Highly Cited
1990
Highly Cited
1990
Proton-proton correlation via carbon-carbon couplings: a three-dimensional NMR approach for the assignment of aliphatic resonances in proteins labeled with carbon-13
directly after the MLEV-17 mixing time in the 2D 13C TOCSY-REVINEPT experiment. This leads to an experiment in which 13C N M R… 
Highly Cited
1986
Highly Cited
1986
Complete Proton and Carbon-13 NMR Assignment of the Alkaloid Gephyrotoxin through the Use of Homonuclear Hartmann-Hahn and Two-Dimensional NMR Spectroscopy
Three different types of modem NMR techniques have been used to obtain a complete proton and carbon- 13 assignment of the… 
Highly Cited
1985
Highly Cited
1985
The Effect of Energy Intake and Expenditure on the Recovery of 13CO2 in the Parenterally Fed Neonate during a 4-Hour Primed Constant Infusion of NAH13CO3
ABSTRACT: The use of 13CO2 excretion to measure the oxidation of 13CO2 labeled substrates is increasing as it is both noninvasive… 
Highly Cited
1983
Highly Cited
1983
Nuclear Overhauser Effects and circular Dichroism as Probes of \beta.-turn Conformations in Acyclic and Cyclic Peptides with Pro-X Sequences
Nuclear Overhauser effects (NOE) and (CD) techniques have been used to probe \beta-turn conformations in acyclic and cyclic… 
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