incomplete Freund's adjuvant

Known as: Freund's incomplete adjuvant, IFA 
A mixture of oil and water that is combined with a specific antigen to boost the immune response to that antigen. It is being studied in… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1966-2017
05019662017

Papers overview

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2011
2011
In experimental tumor immunotherapy, incomplete Freund's adjuvant (IFA) has been considered as the "gold standard" for T-cell… (More)
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2010
Highly Cited
2010
Neutrophils modulated Ag presentation following immunization with Ags in CFA or IFA or alum. The neutrophils had an important… (More)
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2008
Highly Cited
2008
BACKGROUND It is now emerging that for vaccines against a range of diseases including influenza, malaria and HIV, the induction… (More)
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Highly Cited
2007
Highly Cited
2007
Therapeutic vaccination trials, in which patients with cancer were vaccinated with minimal CTL peptide in oil-in-water… (More)
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2005
Highly Cited
2005
The induction of potent CD8+ T cell responses by vaccines to fight microbes or tumors remains a major challenge, as many… (More)
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2002
2002
Freund's incomplete adjuvant (IFA), an aqueous/oil emulsion that is widely used in combination with antigenic proteins and… (More)
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2000
2000
Injection of autoantigens in IFA has been one of the most effective ways of preventing experimental, T cell-mediated, autoimmune… (More)
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Highly Cited
1999
Highly Cited
1999
Traditionally, protein Ags have been injected in CFA (oil with inactivated mycobacteria) to induce immunity and with IFA (oil… (More)
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1998
1998
The water-in-oil emulsion adjuvants developed by Jules Freund and coworkers have been, and continue to be, used in research and… (More)
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1997
Highly Cited
1997
Synthetic oligodeoxynucleotides (ODN) that contain unmethylated CpG motifs (CpG ODN) induce macrophages to secrete IL-12, which… (More)
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