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immunomycin

Known as: changchuanmycin, tacrolimus related compound A, 15,19-Epoxy-3H-pyrido(2,1-c)(1,4)oxaazacyclotricosine-1,7,20,21(4H,23H)-tetrone, 8-ethyl-5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-hexadecahydro-5,19-dihydroxy-3-(2-(4-hydroxy-3-methoxycyclohexyl)-1-methylethenyl)-14,16-dimethoxy-4,10,12,18-tetram 
National Institutes of Health

Related topics

Related topics

6 relations

Broader (3)

Anti-Bacterial AgentsImmunosuppressive AgentsTacrolimus

Narrower (2)

FK 520FR 900520
analogs & derivatives

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2012
Highly Cited
2012
Determination of four immunosuppressive drugs in whole blood using MEPS and LC-MS/MS allowing automated sample work-up and analysis.
2006
2006
The Immunosuppressant Cyclosporin A Antagonizes Human Formyl Peptide Receptor through Inhibition of Cognate Ligand Binding1
Cyclosporin A (CsA) is a fungus-derived cyclic undecapeptide with potent immunosuppressive activity. Its analog, cyclosporin H… 
Highly Cited
2003
Highly Cited
2003
Calcineurin Directs the Reciprocal Regulation of Calcium Entry Pathways in Nonexcitable Cells*
The reciprocal regulation of noncapacitative and capacitative (or store-operated) Ca2+ entry in nonexcitable cells (Mignen, O… 
2002
2002
A New Substrate Specificity for Acyl Transferase Domains of the Ascomycin Polyketide Synthase in Streptomyces hygroscopicus *
Ascomycin (FK520) is a structurally complex macrolide with immunosuppressant activity produced byStreptomyces hygroscopicus. The… 
2002
2002
Genetically Engineered Analogs of Ascomycin for Nerve Regeneration
The polyketides FK506 (tacrolimus) and FK520 (ascomycin) are potent immunosuppressants that function by inhibiting calcineurin… 
2001
2001
Ascomycin: an advance in the management of atopic dermatitis
The demonstration that topical glucocorticosteroids are an effective treatment for atopic dermatitis was one of the major… 
Review
2000
Review
2000
Ascomycins: promising agents for the treatment of inflammatory skin diseases
Ascomycin derivatives represent a novel class of anti-inflammatory macrolactams currently under development for the treatment of… 
1999
1999
Computer-assisted constitutional assignment of large molecules: COCON analysis of ascomycin.
[structure: see text] The computer-assisted constitutional assignment of ascomycin (1) is discussed. This example demonstrates… 
1992
1992
Conformation of two non‐immunosuppressive FK506 analogs when bound to FKBP by isotope‐filtered NMR
1991
1991
Biosynthesis of the immunosuppressant immunomycin: the enzymology of pipecolate incorporation.
Immunomycin, an immunosuppressant closely related to FK 506, contains a pipecolate residue in amide linkage with an acyl group in… 
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