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FK 520

Known as: FK-520 
National Institutes of Health

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2 relations

Broader (2)

Tacrolimusimmunomycin

Papers overview

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2005
2005
CP-123,369: A potent, orally active immunosuppressive agent
A well tolerated immune suppressant with efficacy comparable to cyclosporin A (CsA) and FK-506, both of which have significant… 
2003
2003
In vitro hypoxia and excitotoxicity in human brain induce calcineurin–bcl-2 interactions
Review
2001
Review
2001
Combinatorial biosynthesis in microorganisms as a route to new antimicrobial, antitumor and neuroregenerative drugs.
Combinatorial biosynthesis utilizes the genes of biosynthetic pathways that produce microbial products to create novel chemical… 
1995
1995
Induction of CD5 on B and T cells is suppressed by cyclosporin A, FK-520 and rapamycin.
The expression of CD5 can be induced on murine B-2 cells by anti-IgM, a recognized analog of thymus-independent 2 type (TI-2… 
1995
1995
Tau phosphorylation in brain slices: pharmacological evidence for convergent effects of protein phosphatases on tau and mitogen-activated protein kinase.
Tau is a neuron-specific, microtubule-associated protein that forms paired helical filaments (PHFs) of Alzheimer's disease when… 
1994
1994
Purification of FKBP‐70, a novel immunophilin from Saccharomyces cerevisiae, and cloning of its structural gene, FPR3
Highly Cited
1994
Highly Cited
1994
Calcineurin-mediated protein dephosphorylation in brain nerve terminals regulates the release of glutamate.
In response to Ca2+ entry, several prominent brain nerve terminal phosphoproteins undergo dephosphorylation, but the relation… 
1994
1994
Isolation and characterization of the major equilibrium product of FK-520.
The existence of an isomeric form in equilibrium with the major component of FK-520 in polar solutions has been demonstrated… 
1991
1991
Effects of the immunosuppressant FK-506 and its analog FK-520 on hepatic and renal cytochrome P450 mixed-function oxidase.
1990
1990
Mikrobielles Transformationsprodukt FK-520
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