imiglucerase

Known as: imiglucerase [Chemical/Ingredient] 
 
National Institutes of Health

Papers overview

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2015
2015
BACKGROUND The mainstay of treatment for Gaucher's disease type 1 is alternate-week infusion of enzyme replacement therapy (ERT… (More)
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2013
2013
OBJECTIVE We studied the effect of long-term alglucerase/imiglucerase (Ceredase®/Cerezyme®, Genzyme, a Sanofi company, Cambridge… (More)
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2013
2013
Velaglucerase alfa is a glucocerebrosidase produced by gene activation technology in a human fibroblast cell line (HT-1080), and… (More)
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2011
2011
BACKGROUND In Gaucher disease (GD), acid-β-glucosidase (GBA1) gene mutations result in defective glucocerebrosidase and variable… (More)
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2010
2010
Gaucher disease is the first lysosomal disorder for which clinically effective enzyme replacement therapy has been introduced… (More)
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Highly Cited
2008
Highly Cited
2008
Progressive skeletal disease accounts for some of the most debilitating complications of type 1 Gaucher disease. In this 48-month… (More)
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2008
2008
To assess the extent to which patients with type 1 Gaucher disease (GD1) receiving individualized enzyme replacement therapy with… (More)
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2007
2007
PURPOSE Gaucher disease (GD) is an autosomal recessive lysosomal disorder caused by a deficiency of glucocerebrosidase. The… (More)
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Highly Cited
2006
Highly Cited
2006
UNLABELLED The effect of ERT with imiglucerase on BMD in type 1 GD was studied using BMD data from the International… (More)
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1995
1995
Gaucher's disease, the most common sphingolipidosis, is caused by deficiency of the lysosomal enzyme glucocerebrosidase. Therapy… (More)
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